نتایج جستجو برای: birbeck granule
تعداد نتایج: 31267 فیلتر نتایج به سال:
effects of formulation parameters on the fractional release profile of diclofenac sodium from matrices having the manufacturing formulation ingredients are studied. as a content of cetyl alcohol (rate controlling agent) in the matrix increases, the fractional release decreases. the fractional release increases either by increasing sucrose content outside the granule or by decreasing sucrose con...
Langerin is required for the biogenesis of Birbeck granules (BGs), the characteristic organelles of Langerhans cells. We previously used a Langerin-YFP fusion protein having a C-terminal luminal YFP tag to dynamically decipher the molecular and cellular processes which accompany the traffic of Langerin. In order to elucidate the interactions of Langerin with its trafficking effectors and their ...
Effects of formulation parameters on the fractional release profile of diclofenac sodium from matrices having the manufacturing formulation ingredients are studied. As a content of cetyl alcohol (rate controlling agent) in the matrix increases, the fractional release decreases. The fractional release increases either by increasing sucrose content outside the granule or by decreasing sucrose...
Langerin is a C-type lectin expressed by a subset of dendritic leukocytes, the Langerhans cells (LC). Langerin is a cell surface receptor that induces the formation of an LC-specific organelle, the Birbeck granule (BG). We generated a langerin(-/-) mouse on a C57BL/6 background which did not display any macroscopic aberrant development. In the absence of langerin, LC were detected in normal num...
Kevin Robertson, Kathy Kopnisky, Jens Mielke, Kuku Appiah, Colin Hall, Richard Price, Johnstone Kumwenda, Cecelia Kanyama, Farida Amod, Christina Marra, Terrie Taylor, Umesh Lalloo, Jennifer Jelsma, Penny Holding, Michael Boivin, Gretchen Birbeck, Noelene Nakasujja, Ian Sanne, Thomas D. Parsons, Amanda Parente, and Karen Tucker, on behalf of the Assessment of NeuroAIDS in Africa Conference Part...
Adult histiocytosis X involving the CNS caused progressive spastic paraparesis. The diagnosis was made by immunoreactive anti-S100 protein antibody staining and from the presence of Birbeck granules in biopsy specimens of skin lesions. Neuropathological examination showed massive proliferation and infiltration of S-100 containing histiocyte-like cells and reactive astrocytes throughout the CNS.
Indeterminate cell tumor (ICT) is a rare neoplastic dendritic cell disorder that has been poorly defined due to its rarity and poorly understood histogenesis and pathogenesis. It is characterized by a proliferation of dendritic cells, which mimic Langerhans cells immunophenotypically (positive for CD1a and S-100 protein), but lack Birbeck granules characteristic of Langerhans cells. The clinica...
DEFINITION The histopathologic characteristics of ECD overlap xanthogranuloma and distinctions between the two are made on clinical and radiologic findings. Lipid-laden histocytes with foamy or eosinophilic cytoplasm infiltrate bones and various organs and generate a fibroblastic response that leads to critical organ failure. The histocytes are CD68+, Factor XIIIa+ CD1a-, S100-, and lack Birbec...
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