Recently, antimicrobial peptides have been introduced as potent antibiotics with a wide rangeof antimicrobial activities. They have also exhibited other biological activities, including antiinflammatory,growth stimulating, and anti-cancer activities. In this study, an analog of MagaininII was designed and produced as a recombinant fusion protein. The designed sequence containe...

Recently, antimicrobial peptides have been introduced as potent antibiotics with a wide rangeof antimicrobial activities. They have also exhibited other biological activities, including antiinflammatory,growth stimulating, and anti-cancer activities. In this study, an analog of MagaininII was designed and produced as a recombinant fusion protein. The designed sequence containe...

      A series of angiotensin II (A II) receptor antagonist of some substituted 5-(biphenyl-4-ylmethyl) pyrazole were subjected to QSAR analysis using Hansch and Fujita-Ban model, by using combination of thermodynamic, electronic, spatial descriptor and presence or absence of substituent respectively. Several QSAR model were obtained using stepwise regression analysis. Two models from both the ...

although, coumarins are a group of compounds which are naturally found in some plants, they can be synthetically produced as well. because of their diverse derivatives, origin and properties most of them can be used for medicinal purposes. for example, they can be used against fungal diseases or in studying structure and biological properties of antifungal agents to discover new compounds with ...

a series of angiotensin ii (a ii) receptor antagonist of some substituted 5-(biphenyl-4-ylmethyl) pyrazole were subjected to qsar analysis using hansch and fujita-ban model, by using combination of thermodynamic, electronic, spatial descriptor and presence or absence of substituent respectively. several qsar model were obtained using stepwise regression analysis. two models from both the method...

background and objectives: helicobacter pylori is the causative agent of peptic ulcer disease and a co-factor in development of gastric malignancies. lps are among toxic substances produced by h. pylori exhibiting low endotoxic activity compared to typical bacterial lps. the aim of this study was to investigate bioactivity of lps produced by different serotypes of helicobacter pylori compared t...

seven geographic isolates of helicoverpa armigera npv were characterized by pcr-rflp techniques and their comparative virulence to second instar larvae of h. armigera (hã¼bner) were compared before and after exposure to simulated sunlight as well as open weather conditions on cotton and tomato plants. the pcr products of 25k fp region showed no difference among the isolates (780 bp). the pcr am...