background and objectives: biofilm formation is an important virulence factor for methicillin-resistant staphylococcus aureus (mrsa). fosfomycin is a borad-spectrum antibiotic with inhibitory effects on biofilm production and β-chloro-l-alanine (β-cla) is an amino acid analog. the aim of this study was to determine effect of the combination of fosfomycin and β-cla on biofilm production by mrsa ...

The natural transmission of Yersinia pestis is reliant upon biofilm blockage of the flea vector. However, the environmentally-responsive adaptive regulators which facilitate Y. pestis biofilm production in accordance with the flea midgut milieu are not well understood. We seek to establish the impact of available carbon source metabolism and storage upon Y. pestis biofilm production. Our findin...

Background and Objective: Despite the critical importance of catheter as an indwelling medical device, its prolonged utilization in hospitalized patients may lead to infection. This study aimed to identify distribution of uropathogenic bacteria isolated from catheterized uro-oncology patients, their biofilm production, and antimicrobial resistance patterns to generally -used antibiotics. Mater...

Objective(s):Staphylococcus aureus is a Gram-positive pathogen, well known for its resistance andversatile lifestyle. Under unfavourable conditions, it adapts biofilm mode of growth. For staphylococcal biofilm formation, production of extracellular polymeric substances (EPS) is a pre-requisite, which is regulated by ica operon-encoded enzymes. This study was designed to know the impact of ascor...

Objective(s) Methicillin-resistant Staphylococcus aureus (MRSA) is an important cause of nosocomial and community infections. Biofilm formation, mediated by a polysaccharide intercellular adhesin (PIA) and encoded by the ica operon, is considered to be an important virulence factor in both S. epidermidis and S. aureus. However, the clinical impact of the ica locus and PIA production is less w...

Background and Purpose: Today, treatment of life-threatening fungal infections, caused by Candida species, has become a major problem. In the present study, we aimed to evaluate the antifungal susceptibility patterns of different clinical Candida isolates, determine the virulence factors in multi-drug resistant (MDR) Candida species, and assess the anti-biofilm activity of Elettaria cardamomum ...

background and purpose: today, treatment of life-threatening fungal infections, caused by candida species, has become a major problem. in the present study, we aimed to evaluate the antifungal susceptibility patterns of different clinical candida isolates, determine the virulence factors in multi-drug resistant (mdr) candida species, and assess the anti-biofilm activity of elettaria cardamomum ...

conclusions the remarkable rates of biofilm production ability among clinically isolated staphylococci emphasize the necessity of more effective infections control policies to prevent biofilm formation on medical devices and hospital environmental surfaces. background biofilm formation capacity is recognized as an important virulence factor in staphylococci that makes the organisms more resista...