In this paper, we present the design of four different circular bioassay platforms, which are suitable for homogeneous microwave heating, using theoretical calculations (i.e., COMSOL™ multiphysics software). Circular bioassay platforms are constructed from poly(methyl methacrylate) (PMMA) for optical transparency between 400-800 nm, has multiple sample capacity (12, 16, 19 and 21 wells) and mod...

This work proposes an outstanding screening magneto-bioassay for the early identification of bovine subclinical mastitis. Haptoglobin (Hp) was used as a promising biomarker diagnosis To this end, novel chitosan-modified magnetic particles, coated with haemoglobin-modified polyaniline (MNPs@Chi/PANI-Hb), have been integrated in sensitive electrochemical Hp bioassay. Haemoglobin bioreceptor due t...

In this paper, we have reported that split ring resonators (SRRs) structures can be used for bioassay applications in order to further improve the assay time and sensitivity. The proof-of-principle demonstration of the ultrafast bioassays was accomplished by using a model biotin-avidin bioassay. While the identical room temperature bioassay (without microwave heating) took 70 min to complete, t...

Two in vivo bioassay methods, a rat medium-term liver bioassay and a rat multiorgan bioassay, can be used for detecting carcinogenic or modifying potentials of endocrine active substances (EASs) on endocrine disruption (ED). The first bioassay, the rat mediumterm liver bioassay, is fundamentally based on the two-step hypothesis of liver carcinogenesis; initiation with diethylnitrosamine (DEN, 2...