OBJECTIVE To assess the influence of glutathione S-transferases M1 and T1 (GSTM1 and T1) genotype on the risk of bladder cancer in patients with urinary bilharziasis. MATERIALS AND METHODS This study was designed as a case-control study that involved 60 individuals who were enrolled into 3 equal groups. The first one included patients with bilharzial bladder cancer, the second one had those w...

112 cases, of varying ages, which were diagnosed as having carcinoma of the bladder by cystoscopy and biopsy from the tumor, were investigated for the presence of alphafetoprotein (AFP) in the sera. 59 (52.6%) out of the total, showed positive results, and no false positive results occured. Radioimmunoassay was capable of increasing the positivity rate still further. All of the cases were prove...

McCULLY, R. M. & KRUGER, S. P. Observations on bilharziasis of domestic ruminants in South Africa. Onderstepoort J. vet . Res. 36 (1), 129-162 Bilharziasis of 100 sheep and 14 cattle caused by Schistosoma mattheei Veglia & Le Roux, 1929, was studied in detail from the histopathological aspect. The ovine cases included natural as well as experimentally infested animals. The most significant chan...

In addition to the classical manifestations, bilharziasis may present with features which are atypical and which may simulate other conditions. In such cases the value of the previous history cannot be overemphasized, immunodiagnostic procedures are useful pointers in diagnosis but in general treatment should be undertaken only after ova of the parasites have been found.

BACKGROUND Bladder cancer represents the fifth most common malignancy worldwide and a major cause of cancer-related morbidity and death. Incidence and mortality rates have remained relatively constant over the past four decades. Urothelial bladder cancers have identified multiple risk factors. AIM We aimed at evaluating the expression of the FGFR3 protein and gene amplification in the urothel...

Bilharziasis is a parasitic disease that affects the urinary tract and intestines. Finding bilharzia in joints is exceptional. We report two cases of Malagasy patients living in a highly endemic bilharziasis area and having chronic arthritis due to bilharziasis. The first case was a 32-year-old man presenting with a clinical picture of spondylitis with chronic oligoarthritis and paroxysmal asym...