Continuing Avastin beyond the time when advanced crc gets worse helps patients, according to new study reports. Patients who continued to receive avastin with a new chemotherapy regimen after their cancer first progressed lived almost 12 months longer than patients who got more chemo but stopped avastin. Both groups did better than those who had no further treatment at all. The BRITE (Bevacizum...

OBJECTIVE To assess the effectiveness of intravitreal injection of Bevacizumab in the treatment of diabetic macular edema. METHODS This case series was conducted at Department of Ophthalmology, Jinnah Post Graduate Medical Centre (JPMC), Karachi. The duration of study was six months from May 26, 2011 to November 25, 2011. The study group comprised of 54 patients of the Diabetic Macular Edema ...

Avastin® (bevacizumab) is a protein drug widely used for cancer treatment although its further use is questionable due to serious side effects reported. As no systematic proteomic study on posttranslational modifications (PTMs) was reported so far, it was the aim of the current study to use a gel-based proteomics method for determination of Avastin®-protein(s). Avastin® was run on two-dimension...

Background: A pterygium is a fleshy, wing-shaped growth from the conjunctiva, crossing over limbus onto cornea. The tissue fibrovascular and can occur nasal or temporal It be bilateral process asymmetric with one eye affected by larger than other. Objectives: To compare between Subconjunctival injection of bevacizumab (Avastin) conjunctival autograft in treatment primary pterygium. Patients Met...

B.V. is a 53-year-old nulliparous woman who was initially diagnosed with recurrent stage 3C epithelial ovarian carcinoma in 2011. She underwent a hysterectomy, bilateral salpingo-oophorectomy, and optimal tumor debulking. Adjuvant therapy consisted of a clinical trial (Gynecologic Oncology Group [GOG] 262) protocol of 6 cycles of IV carboplatin, paclitaxel, and bevacizumab (Avastin) followed by...

Intracameral injection of bevacizumab (Avastin) helped in the successful regression of an anterior chamber neovascular membrane in a painful blind eye. The effect was persistent even after six months of follow-up. This is the first report on intracameral administration of bevacizumab with six months of follow-up.

Bevacizumab (Avastin, Genentech) is a recombinant humanised, full length, antiVEGF monoclonal antibody that binds all isoforms of VEGF-A. It has been shown to prolong survival of patients with advanced colon cancer when combined with 5-fluorouracil. In this report, we describe the effect of bevacizumab in two patients with choroidal neovascularisation (CNV) secondary to pathological myopia, whi...

PURPOSE To evaluate the additional therapeutic effect of single intravitreal bevacizumab injection on standard laser treatment in the management of proliferative diabetic retinopathy. METHODS A prospective, fellow-eye sham controlled clinical trial was conducted on 80 eyes of 40 high-risk characteristic proliferative diabetic retinopathy type II diabetics. All cases received standard laser tr...

1. Bevacizumab Not Helpful for Stage III Colorectal Cancer 2. Screening for KRAS and BRAF Mutations 3. Aspirin May Help Older Colon Cancer Patients Live Longer 4. Hypertension Means Better Survival When Treated with Avastin 5. Reduced Risk of Colorectal Cancer With Use of Oral Bisphosphonates 6. Xelox and Avastin Followed by Single Agent Avastin as Maintenance Therapy in First Line Treatment of...