Infectious diseases are the major cause of morbidity and mortality caused by Pseudomonas aeruginosa (P. aeruginosa) and Acinetobacter baumannii (A. baumannii) and have successfully evolved numerous strategies for resisting the action of many antibacterial drugs. They harbor several drug resistant mechanisms such as target alteration, efflux pump, low intrinsic susceptibility and cross-resistanc...

1 Laboratoire Universitaire de Biodiversité et d’Ecologie Microbienne (LUBEM)-EA n° 3882-IFR148, Université de Bretagne Occidentale, Brest, France 2 UFR d’Odontologie, Université de Bretagne Occidentale/ Service d’Odontologie, Pôle Organes des sens, CHRU Brest, France 3 Laboratoire de bactériologie-virologie, Pôle Biologie, CHRU Brest, France 4 Service de Pédiatrie, Pôle FemmeMère-Enfant, CHRU ...

Nhiễm khuẩn huyết (NKH) là một tình trạng nhiễm trùng cấp tính nặng, gây ra cái chết cho hàng triệu người mỗi năm trên toàn thế giới. Sự lan tràn các chủng vi kháng sinh đang vấn đề bách nhất hiện nay, trực tiếp làm giảm hiệu quả điều trị và sức khỏe bệnh. Đối tượng phương pháp nghiên cứu: Thiết kế cứu mô tả cắt ngang nhằm xác định thường gặp mức độ của chúng trong cấy máu tại Bệnh viện đa khoa...

background and objective: to evaluate extended spectrum betalactamase (esbl) positive strains of klebsiella pneumonia and escherichia coli in positive bacterial cultures. materials and methods: in this analytical cross-sectional study, between march 2006 and march 2007, 170 bacterial isolates including 133 cases of e. coli and 37cases of k. pneumonia were examined. all cases underwent double di...

Results Among 979 strains isolated during this period, 10.82 % (106) were ESBL producers. These bacteria were isolated in 94.33% in the inpatients specimens. Their distribution was essentially in the ICU (22.64%),the surgery (20.75%) and the pediatrics 21.21%.They were more frequently isolated from urines (36.79%), pus (33%), peritoneal liquid (15,15%)and bacteremia (12,26%).This betalactamase ...

CENTA is a newly synthesized, beta-lactamase-labile, chromogenic cephalosporin reagent which changes color from light yellow (K maximum ca. 340 nm) to chrome yellow (A maximum ca. 405 nm) concomitant with hydrolysis of the betalactam ring. This compound offers promise as a diagnostic reagent comparable to other chromogens (PADAC and nitrocefin) for the early detection of betalactamase-producing...

among Klebsiella Pneumoniae in Chennai. Indian J Med Microbiol 2002;20:92-5. 3. Clinical and Laboratory Standards Institute. Performance standards for antimicrobial disk tests; Approved Standards, 9th ed. CLSI Document M2A9, Vol. 26 No 1. Wayne PA: 2006. 4. Motta RN, Oliveira MM, Magalhaes PS, Dias AM, Aragao LP, Forti AC, et al. Plasmid mediated extended spectrum betalactamase producing strain...

The increasing prevalence of multiresistant Gram-negative bacteria of the Enterobacteriaceae family in Europe is a worrisome phenomenon. Extended spectrum betalactamase-producing Escherichia coli strains are widespread in the community and are frequently imported into the hospital. Of even more concern is the spread of carbapenem-resistant strains of Klebsiella spp. from regions where they are ...

BACKGROUND & OBJECTIVE Metallo beta-lactamase (MBL)-mediated resistance to carbapenems is an emerging threat in hospital isolates of Pseudomonas aeruginosa. Though there are several screening methods to detect this enzyme production, the National Committee for Clinical Laboratory Standards (NCCLS) does not have performance standards documented so far. There is not enough information from the In...