A novel Förster resonance energy transfer (FRET) fluorescence "off-on" system based on the highly specific, sensitive and effective C-C bond cleavage of certain dihydropyridine derivatives was reported for real-time quantitative imaging of nitric oxide (NO). 1,4-Dihydropyridine was synthesized as a novel linker which could connect customized fluorophores and their corresponding quenchers. The s...

A novel Förster resonance energy transfer (FRET) fluorescence “off–on” system based on the highly specific, sensitive and effective C–C bond cleavage of certain dihydropyridine derivatives was reported for real-time quantitative imaging of nitric oxide (NO). 1,4-Dihydropyridine was synthesized as a novel linker which could connect customized fluorophores and their corresponding quenchers. The s...

Novel derivatives of chromenone bearing an N -carbamothioyl moiety were synthesized and evaluated for their soybean 15-LOX inhibitory activity. Synthesis of the target compounds was started from 7-hydroxy-2H -chromen-2-one. It was reacted with 1-fluoro-2(4)-nitrobenzene to obtain the corresponding nitrophenoxy-chromenone derivative. Reduction of the nitro group was achieved in the presence of Z...

2-Phenyl-1-(3?,5?-dichloro-2?-benzo(b)thiophenoylamino)-4-arylidine-5-imidazolones (2a-j) were prepared from the 2-hydrazinocarbonyl-3,5-dichlorobenzo[b]thiophene 1 by the reaction with different oxazolinone which were prepared by the condensation of substituted benzaldehyde with benzoyl glycine in presence of sodium acetate and acetic anhydride. Reaction of 1 with different aromatic isothiocya...

2-phenyl-1-(3?,5?-dichloro-2?-benzo(b)thiophenoylamino)-4-arylidine-5-imidazolones (2a-j) were prepared from the 2-hydrazinocarbonyl-3,5-dichlorobenzo[b]thiophene 1 by the reaction with different oxazolinone which were prepared by the condensation of substituted benzaldehyde with benzoyl glycine in presence of sodium acetate and acetic anhydride. reaction of 1 with different aromatic isothiocya...

Background: Topical retinoid based combinations are recommended to enhance the outcome of acne treatment. Adapalene-benzoyl peroxide (BPO) combination gel was approved in 2009 for acne treatment. The aim of this study was to evaluate the efficacy and tolerability of adapalene 0.1%-benzoyl peroxide 2.5% combination gel compared to adapalene 0.1% gel monotherapy and benzoyl peroxide 2.5% gel mono...

ABSTRACT. In this study, five different thiourea derivatives were synthesized from aryl amines according to the reported method. 1-Benzoyl-3-(4-methoxyphenyl)thiourea (2) was confirmed with single crystal XRD analysis while 1-benzoyl-3-phenylthiourea (1), 1-benzoyl-3-(4-hydroxyphenyl)thiourea (3), 1-benzoyl-3-(2-nitrophenyl) (4) and 1-benzoyl-3-p-tolylthiourea (5) elucidated FTIR NMR techniques...

moringaceae, a monogeneric family in capparales (glucosinolate-containing species), includes 14 species. one of them is moringa peregrina (forssk.) fiori., a small tree, which grows in south east of iran. volatile constituents of seed coat and stem of m. peregrina were determined by gc and gc/ms. moreover, extracts of seed and different cultured cells were analyzed by tlc and gc. three volatile...

In the title compound, C(29)H(25)ClO(4), the dihedral angle between the benzene rings of the 2,4,6-trimethyl-benzoyl group and the 4-chloro-benzoyl group is 65.19 (9)°. The dihedral angles between the naphthalene ring system and the benzene rings of the 2,4,6-trimethyl-benzoyl group and the 4-chloro-benzoyl group are 85.66 (8) and 69.48 (8)°, respectively. In the crystal, two types of inter-mol...