Plexiform fibrohistiocytic tumor is an intermediate malignant tumor situated in superficial soft tissues. It affects children and young adults. The tumor is most commonly located on upper extremities, whereas involvement of back region is rare. Mitotic activity is generally low (~3/10 HPF). It is rare, but it can exhibit aggressive behavior, so total excision with clear surgical margins and lon...

Neurothekeomas are rare, benign dermal tumors of presumed fibrohistiocytic lineage. They present multiple differential diagnoses, making their identification challenging at the dermatological and anatomopathological examination. We report case a 28-year-old man who presented hardened papule growth on left upper eyelid with histopathology immunohistochemistry suggestive neurothekeoma.

Benign plexiform lesion may describe a rare tumor based on morphological features. Plexiform arrangement may suggest lesions which are spindled and focally show some whorling and fascicular pattern [1]. Literature has provided a vast differential diagnosis of plexiform lesion some of which include schwannoma, fibrohistiocytic tumors, angiomyxoid tumors, fibromyxoma [25]. Plexiform neurofibroma ...

background: studies have shown that obese individuals are at increased risk of breast cancer development and poorer prognosis. leptin, an adipose tissue-derived hormone, has pro-inflammatory and proliferative effects and a well-established association with several comorbidities of obesity. this study was designed and conducted to compare the serum levels of leptin in patients with malignant and...

The spectrum of lipomatous lesions ranges from benign to highly malignant disease. Differentiation between these lesions is important to indicate prognosis and choose the most appropriate treatment. Hemosiderotic fibrohistiocytic lipomatous lesion (HFLL) is a rare subtype of lipomatous tumor. The diagnosis is usually based on clinical, histological, and immunohistochemical information. Where ma...

Dr. Enzinger was the primary editor of the first soft tissue World Health Organization (WHO) book in 1969, entitled “Histological Typing of Soft Tissue Tumours.” Although he had not yet described angiomatoid “malignant” fibrous histiocytoma (A(M)FH), giant cell fibroblastoma (GCF), or plexiform fibrohistiocytic tumor (PFHT), he had already considered the concept of a fibrous tumor of intermedia...

introduction: different imaging modalities are used to evaluate salivary gland diseases, including tumors. ultrasonography (us) is the preferred method on account of its ease of use, affordability, safety profile, and good tolerance among patients. the aim of this study was to evaluate the role of us in differentiating malignant from benign parotid tumors, in the context of previous controversy...

A benign fibrous histiocytoma (BFH) is one of the fibrohistiocytic groups of soft-tissue tumors for which spinal involvement is extremely rare. To the best of our knowledge, most spine-originating BFHs are bone tumors. We report the first case of BFH occurring in the intraspinal extradural space on the lumbar spine. A 66-year-old female presented with severe claudication symptom. The preoperati...

benign renal cystic adenoma with out malignant features is a very rare entity. a 75 year old male with obstructive lower tract symptoms and vague flank pain was admitted and planned for nephrectomy of non functional kidney -due to long term nephrolithiasis- intra operative finding was a cystic hydronephrotic kidney filled by thick mucous secretions which turned out to be a cyst adenoma of kidne...