Butter fat has been found to be a very complex fat, containing in its glyceride linkages a large number of fatty acids. Since some of these acids are present in very small amounts, they have in the past been frequently overlooked. This is especially true of the fatty acids of higher molecular weight than stearic acid. Hilditch and Jones (l), Hilditch and Sleightholme (2), and others have report...

theory. Further, trypsin and other proteolytic enzymes, by destroying the protein part of thromboplastin, would increase its dissociation and speed the transfer of cephalin to prothrombin, thus providing a mechanism for the action of trypsin on the compound, the practical significance of which Ferguson has stressed. In the case of those clotting factors which are enzymes, the theory becomes the...

Fatty acid synthase (FASN) is the metabolic enzyme responsible for the endogenous synthesis of the saturated long-chain fatty acid palmitate. In contrast to most normal cells, FASN is overexpressed in a variety of human cancers including cutaneous melanoma, in which its levels of expression are associated with a poor prognosis and depth of invasion. Recently, we have demonstrated the mitochondr...

Long-chain alcohols are synthesized in the mouse preputial gland tumor (ESR-586) by NADPH:acyl-CoA oxidoreductase. In this study, a series of labeled acids was tested as substrates for the oxidoreductase in a cell-free system from the tumor, and the distribution of label into alcohols, waxes, and other products was determined. The system contained the labeled acid, an acyl-CoA-generating system...

Intravenous injections of various fatty acids in rabbits caused marked thrombopenia lasting 1-2 hr. The most active saturated fatty acids were myristic acid (14:O) and lauric acid (12: 0). Activity decreased with increasing and decreasing chain length, but behenic acid (22 : 0) had, on a molar basis, activity similar to that of lauric acid. Of the unsaturated fatty acids, oleic acid (18: 1) was...

The physico-chemical properties of oil from Moringa oleifera seeds from India were determined in the present study. The petroleum ether extracted oil ranged from 27.83 - 45.07% on kernel basis and 15.1-28.4% on whole seed basis in 20 different clones. Leaves and pods showed a good source of vitamin C. Oleic acid (C18:1) has been found to be the major fatty acid being 78.91-85.52% as compared to...

BACKGROUND Tuberculosis (TB) is a chronic wasting inflammatory disease characterized by multisystem involvement, which can cause metabolic derangements in afflicted patients. Metabolic signatures have been exploited in the study of several diseases. However, the serum that is successfully used in TB diagnosis on the basis of metabolic profiling is not by much. METHODS Orthogonal partial least...