نتایج جستجو برای: bee venom

تعداد نتایج: 22003  

2016
Chung Eui You Seok Hoon Moon Kwang Hoon Lee Kyu Han Kim Chun Wook Park Seong Joon Seo Sang Hyun Cho

BACKGROUND Atopic dermatitis (AD) is a common, complex disease that follows a chronic relapsing course and significantly affects the quality of life of patients. Skin barrier dysfunction and inflammatory processes induce and aggravate this skin condition. Proper use of an emollient for hydration is a keystone of AD treatment. Bee venom is known to have anti-inflammatory effects and has been wid...

Journal: :Biological & pharmaceutical bulletin 2016
Seeun Park Sedef Erdogan Dahyun Hwang Seonwook Hwang Eun Hye Han Young-Hee Lim

Alopecia is an important issue that can occur in people of all ages. Recent studies show that bee venom can be used to treat certain diseases including rheumatoid arthritis, neuralgia, and multiple sclerosis. In this study, we investigated the preventive effect of bee venom on alopecia, which was measured by applying bee venom (0.001, 0.005, 0.01%) or minoxidil (2%) as a positive control to the...

2016
Andreas Hartmann Julia Müllner Niklaus Meier Helke Hesekamp Priscilla van Meerbeeck Marie-Odile Habert Aurélie Kas Marie-Laure Tanguy Merry Mazmanian Hervé Oya Nissen Abuaf Hafida Gaouar Sabrina Salhi Fanny Charbonnier-Beaupel Marie-Hélène Fievet Damien Galanaud Sophie Arguillere Emmanuel Roze Bertrand Degos David Grabli Lucette Lacomblez Cécile Hubsch Marie Vidailhet Anne-Marie Bonnet Jean-Christophe Corvol Michael Schüpbach

In the present study, we examined the potential symptomatic and/or disease-modifying effects of monthly bee venom injections compared to placebo in moderatly affected Parkinson disease patients. We conducted a prospective, randomized double-blind study in 40 Parkinson disease patients at Hoehn & Yahr stages 1.5 to 3 who were either assigned to monthly bee venom injections or equivalent volumes ...

Journal: :Pediatrics 2013
A I Stritzke P A Eng

BACKGROUND Data on outcome of insect venom immunotherapy in children are rare. OBJECTIVE We investigated the rate of sting recurrence and outcome of Hymenoptera venom anaphylaxis in children of different age groups treated with immunotherapy. METHODS Data from children consecutively referred for anaphylaxis to Hymenoptera venom were collected using a standardized questionnaire. RESULTS Du...

2015
Woo-Ram Lee Sok Cheon Pak Kwan-Kyu Park Ren Lai

Bee venom therapy is a treatment modality that may be thousands of years old and involves the application of live bee stings to the patient's skin or, in more recent years, the injection of bee venom into the skin with a hypodermic needle. Studies have proven the effectiveness of bee venom in treating pathological conditions such as arthritis, pain and cancerous tumors. However, there has not b...

2010
Young Moo Choo Kwang Sik Lee Hyung Joo Yoon Bo Yeon Kim Mi Ri Sohn Jong Yul Roh Yeon Ho Je Nam Jung Kim Iksoo Kim Soo Dong Woo Hung Dae Sohn Byung Rae Jin

Bee venom contains a variety of peptides and enzymes, including serine proteases. While the presence of serine proteases in bee venom has been demonstrated, the role of these proteins in bee venom has not been elucidated. Furthermore, there is currently no information available regarding the melanization response or the fibrin(ogen)olytic activity of bee venom serine protease, and the molecular...

Journal: :Arhiv za higijenu rada i toksikologiju 2009
Nada Orsolić

This study investigated possible growth-inhibiting effects of bee venom applied alone or in combination with a cytotoxic drug bleomycin on HeLa and V79 cells in vitro based on clone formation, cell counting, and apoptosis. Melittin, the key component of bee venom, is a potent inhibitor of calmodulin activity, and also a potent inhibitor cell growth and clonogenicity. Intracellular accumulation ...

2012
Masoumehzaman Alizadehnohi Mohammad Nabiuni Zahra Nazari Zahra Safaeinejad Saeed Irian

Ovarian cancer is considered to be one of the most important causes of death among women. Cisplatin is one of the oldest chemotherapeutical compounds used for treating ovarian cancer. Previous studies have shown the inhibitory effects of bee venom on certain types of cancer. The aim of the present study was to evaluate the cytotoxic effect of bee venom alone and its synergistic cytological effe...

Journal: :iranian journal of allergy, asthma and immunology 0
mohsen hamedani abbas mirshafiey hossein vatanpour mohammad reza khorramizadeh farshid saadat azar berahmeh

controversial immunomodulatory properties of bee venom (bv) have provided an appropriate field for more investigation. the aim of present research was to verify the effects of honeybee venom on matrix metalloproteinase activity and interferon production as well as cell proliferation in monocyte and fibroblast cell lines. the monocyte and fibroblast cell lines (k562, ht-1080, wehi-164) were used...

2013
Daniel Alvarez-Fischer Carmen Noelker Franca Vulinović Anne Grünewald Caroline Chevarin Christine Klein Wolfgang H. Oertel Etienne C. Hirsch Patrick P. Michel Andreas Hartmann

Bee venom has recently been suggested to possess beneficial effects in the treatment of Parkinson disease (PD). For instance, it has been observed that bilateral acupoint stimulation of lower hind limbs with bee venom was protective in the acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of PD. In particular, a specific component of bee venom, apamin, has previously been sh...

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