This study presents a new methodology adapted to the analysis of word rhythmic cues in drummed forms of languages. The semi-automatic beat detection procedure applied to the Manguaré drummed form of the Bora language enabled us to measure inter-beat durations. These were found to correspond to Vowel-to-Vowel intervals (V-to-V) of the associated speech utterances and to differ as a function of t...

In Southeast Asia alpha-thalassemia, beta-thalassemia, hemoglobin (Hb) E and Hb Constant Spring are prevalent. The gene frequencies of alpha-thalassemia reach 30-40% in Northern Thailand and Laos. beta-Thalassemia gene frequencies vary between 1 and 9%. Hb E is the hallmark of Southeast Asia attaining a frequency of 50-60% at the junction of Thailand, Laos, and Cambodia. Hb Constant Spring gene...

OBJECTIVE Changing patterns of immigration to North America, along with improved treatment, have altered the clinical spectrum of thalassemia, one of the world's most common genetic diseases. The new demography of the disease, with its widely variable phenotypes, has implications for its diagnosis, counseling, and management. Characterization of the new spectrum of this ancient disease, now pre...

Mục tiêu nghiên cứu: Mô tả đặc điểm huyết học và tỷ lệ lưu hành gen bệnh tan máu bẩm sinh (thalassemia) của người dân từ 15 – 20 tuổi tại tỉnh Cao Bằng. Phương pháp cắt ngang có phân tích trên đối tượng là 355 Bằng tháng 9/2021 đến 1/2023. Kết quả Tỷ thiếu chung ở 15-20 19,1%; mức độ nặng 1,4%, vừa 7,6%, nhẹ 10,1%; hồng cầu nhỏ nhược sắc 24,8%; sắt đơn thuần 1,4%; 4,2%, bất thường tố 6,2% theo ...

Thalassemia is a hereditary disease caused by abnormalities in red blood cells which the individual has gene disorder that causes reduced production of hemoglobin cells. People with Thalassemia, especially type Major, need routine therapy and medication. These medication activities sometimes cause various problems obstacles lives people thalassemia both physically psychologically. Individuals a...

Thalassemia is a hematological disorder caused by gene mutation that leads to defective synthesis of hemoglobin complex. One the complications thalassemia hypocalcemia which presented with paresthesia, muscle spasm, low-serum calcium, and intracranial calcification. Hypocalcemia can affect thalassemic patients via various mechanisms. Blood transfusion-related transfusion-independent iron overlo...

Thalassemia, an inherited quantitative globin disorder, consists of two types, α– and β–thalassemia. β–thalassemia is a heterogeneous disease that can be asymptomatic, mild, or even severe. Considerable research has focused on investigating its underlying etiology. These studies found DNA hypomethylation in the β–globin gene cluster significantly related to fetal hemoglobin (HbF) elevation. His...

Thalassemia is a chronic disease that can affect quality of life. The purpose this study was to determine the effect family support, transfusion compliance and self-efficacy on life children with thalassemia. This research correlational cross-sectional approach. sample consisted 45 people. Data were collected using questionnaires, statistical analysis descriptive data respondents’ characteristi...

Few literatures have elaborated on the clinical characteristics of children with thalassemia from low-prevalence areas. A retrospective analysis was conducted on children genetically confirmed with thalassemia at Seoul National University Children's Hospital in Korea. Nine children (1α thalassemia trait, 6β thalassemia minor, 2β thalassemia intermedia) were diagnosed with thalassemia at median ...

Thalassemia, a hereditary anemia, has been a major public health problem in Thailand and Southeast Asia for decades, yet the prevalence of thalassemia in Thailand is not decreasing due to lack of awareness of this disease in Thai population, which implied that genetic counseling was a failure. We determined the problems and obstacles in thalassemia counseling in Thailand and proposed the possib...