In this study, we focused on the gait of Parkinson’s disease (PD) and presented a gray box model for it. We tried to present a model for basal ganglia structure in order to generate stride time interval signal in model output for healthy and PD states. Because of feedback role of dopamine neurotransmitter in basal ganglia, this part is modelled by “Elman Network”, which is a neural network stru...

introduction: huntington disease (hd) is a progressive neurodegenerative disease which affects movement control system of the brain. hd symptoms lead to patient’s gait change and influence stride time intervals. in this study, we present a grey box mathematical model to simulate hddisorders. this model contains main physiological findings about bg. methods: we used artificial neural networks (a...

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background: familial idiopathic basal ganglia calcification (ibgc) is a rare neurodegenerative disorder which is usually transmitted as an autosomal dominant trait. ibgc is genetically heterogeneous and slc20a2, on chromosome 8p21.1–8q11.23, is the first gene found in ibgc-affected patients with varied ancestry. on the other hand, several candidate genes for ibgc on chromosome 2q37, including t...

in this study, we focused on the gait of parkinson’s disease (pd) and presented a gray box model for it. we tried to present a model for basal ganglia structure in order to generate stride time interval signal in model output for healthy and pd states. because of feedback role of dopamine neurotransmitter in basal ganglia, this part is modelled by “elman network”, which is a neural network stru...

 ABSTRACT Background: High resolution CT scan has made early diagnosis of intraventricular hemorrhage (IVH) easier. Posttraumatic intraventricular hemorrhage has been reported to a greater extent because of the CT scan. Methods: 904 patients were admitted in the NSICU from March 2001 to March 2002 with severe closed head injury, of those only 31 patients with intraventricular hemorrhage (GCS le...

Neurological tumors, such as gliomas and meningiomas are rarely presented by movement disorders. Early detection of neurological both basal ganglia arising tumors ganglia-sparing ones, presenting with disorders is crucial to prevent any further deficits.

Objectives: To mathematically model the oscillatory behaviour of Basal Ganglia for Parkinson’s disease as well to simulate by using Cell designer and Scilab. Method: The pathway Parkinsons was downloaded from KEGG database studied scilab programming cell tool. In this work, loaded designer, that is working on basis systems biology mark-up language, analysed entire pathway. Findings: oscillary b...