نتایج جستجو برای: barnes maze
تعداد نتایج: 13229 فیلتر نتایج به سال:
Patients with type II lissencephaly, a neuronal migration disorder with ectopic neurons, suffer from severe mental retardation, including learning deficits. There is no effective therapy to prevent or correct the formation of neuronal ectopia, which is presumed to cause cognitive deficits. We hypothesized that learning deficits were not solely caused by neuronal ectopia and that postnatal gene ...
Prolonged early-life seizures are associated with disruptions of affective and cognitive function. Postictal disturbances, temporary functional deficits that persist for hours to days after seizures, have not yet been thoroughly characterized. Here, we used kainic acid (KA) to induce status epilepticus (SE) in immature rats at three developmental stages (postnatal day (P) 15, 21, or 30) and sub...
Background & Aim:Cognitive impairment is one of the age-related mental problems and a typical indicator of neurodegeneration. Eragrostis tremula Hochst. ex Steud. is a commonly used medicinal plant in Nigeria for memory enhancement. This study, therefore, aimed at evaluating the memory-enhancing potential of aqueous ethanolic extract of E. tremula in ...
More than 5,000,000 survivors of traumatic brain injury (TBI) live with persistent cognitive deficits, some of which likely derive from hippocampal dysfunction. Oscillatory activity in the hippocampus is critical for normal learning and memory functions, and can be modulated using deep brain stimulation techniques. In this pre-clinical study, we demonstrate that lateral fluid percussion TBI res...
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