The aim of the present study is to assess and compare the frequencies of the cytochrome P450 CYP2C9 variations in the Baluch ethnic group (n=110) with other ethnic groups. The allele frequencies of CYP2C9*1, CYP2C9*2 and CYP2C9*3 were 80.90%, 11.82% and 7.27%, respectively. 70.90%, 11.82%, 8.18%, 4.55%, 2.73% and 1.82% of subjects were with CYP2C9*1/*1, CYP2C9*1/*2, CYP2C9*1/*3, CYP2C9*2/*2, CY...

BACKGROUND Alpha thalassemia (α-thal) is one of the most common hemoglobinopathies worldwide. The aim of this study was to investigate the spectrum of α-thal mutations among premarital Baluch couples in southeastern Iran. SUBJECTS AND METHODS We assessed 1215 individuals by multiplex gap polymerase chain reaction (gap-PCR) and amplification refractory mutation system (ARMS-PCR). RESULTS Of ...

We read with interest two papers published in the two recent issues of nursing and midwifery studies. Reading these two papers motivated us to write this letter, on the importance of observing several basic requirements in reporting qualitative and quantitative studies. Here, we present our critics, firstly, on the qualitative paper and then, on the quantitative one. In the issue of March 2015,...

There are two constitutional political formations in Iranian Baluchistan. One is the tribe, which is the ultimate kin group to which loyalty is owed (Salzman 2000: Ch. 11). The other is the hakomate, a complex formation consisting of a small ruling elite, settled peasantry, and nomads, and which is integrated on bases other than loyalty (Salzman 1978a). I call the tribe and the hakomate “consti...

Cystic fibrosis (CF) is the most common autosomal recessive disorder caused due to mutation/s in the CFTR gene. The most common mutation in CFTR worldwide is ΔF508 and cystic fibrosis genetic analysis consortium revealed that this mutation is responsible for approximately 66% of all CF chromosomes in the world. Studies looking at the DNA polymorphic haplotypes created by CF linked markers sugge...

OBJECTIVE Boerhaavia elegans L. (Nyctaginaceae) is a medicinal plant used for the treatment of kidney disorders, urinary tract disorders and blood purification in Baluch tribe. The aim of present study is to evaluate the antioxidant property of B. elegans species for the first time. MATERIALS AND METHODS Different parts (leaf, stem and fruit) of the plant were extracted by using various solve...

As we navigate through the third decade of 21st century confronted by a barrage natural disasters with fingers pointed at climate change, what is clear that poor and vulnerable are greatest victims ravages caused changing weather conditions. According to Dr Fahad Saeed in response 2022 monsoon apocalyptic impact on many Pakistanis, “People smallest carbon footprints suffering most...The living ...

Cystic fibrosis (CF) is the most common autosomal recessive disorder caused due to mutation/s in the CFTR gene. The most common mutation in CFTR worldwide is deltaF508 and cystic fibrosis genetic analysis consortium revealed that this mutation is responsible for approximately 66% of all CF chromosomes in the world. Studies looking at the DNA polymorphic haplotypes created by CF linked markers s...

BACKGROUND Ankylosing spondylitis (AS) may manifest with heterogeneous patterns according to ethnic origins. The purpose of this study was to describe the influence of various Iranian ethnic origins on clinical measures in patients with AS. METHODS 0ne hundred sixty-three AS patients diagnosed by modified New York 1984 criteria were enrolled consecutively. The patients were classified into Fa...