نتایج جستجو برای: bacterial barrier

تعداد نتایج: 291925  

Journal: :Investigative ophthalmology & visual science 2011
Julia Klocke Rita N Barcia Susan Heimer Elke Cario James Zieske Michael S Gilmore Bruce R Ksander Meredith S Gregory

PURPOSE CD36 is a Class B scavenger receptor that is constitutively expressed in the corneal epithelium and has been implicated in many homeostatic functions, including the homeostasis of the epidermal barrier. The aim of this study is to determine (1) whether CD36 is required for the maintenance of the corneal epithelial barrier to infection, and (2) whether CD36-deficient mice present with an...

2016
Jonathan Manuel Aguirre Valadez Liliana Rivera-Espinosa Osvely Méndez-Guerrero Juan Luis Chávez-Pacheco Ignacio García Juárez Aldo Torre

Liver cirrhosis is a worldwide public health problem, and patients with this disease are at high risk of developing complications, bacterial translocation from the intestinal lumen to the mesenteric nodes, and systemic circulation, resulting in the development of severe complications related to high mortality rate. The intestinal barrier is a structure with a physical and biochemical activity t...

Journal: :Acta cirurgica brasileira 2015
Elísio Rodrigues Coelho Junior Laura Olinda Bregieiro Fernandes Costa Arinaldo Vasconcelos Alencar Ana Paula Guimarães Barbosa Flávia Crisina Morone Pinto José Lamartine de Andrade Aguiar

PURPOSE To analyze the effectiveness of bacterial cellulose hydrogel as a barrier in preventing postoperative peritoneal adhesion in rat model. METHODS Experimental study with 45 Wistar rats (Rattus norvegicus) that were divided into three groups for the following treatments: A. Saline, B. Oxidized Regenerated Cellulose (ORC) barrier, and C Bacterial Cellulose Hydrogel (BCH) barrier. After 45...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2004
Marc Lecuit D Michael Nelson Steve D Smith Huot Khun Michel Huerre Marie-Cécile Vacher-Lavenu Jeffrey I Gordon Pascale Cossart

Listeria monocytogenes produces severe fetoplacental infections in humans. How it targets and crosses the maternofetal barrier is unknown. We used immunohistochemistry to examine the location of L. monocytogenes in placental and amniotic tissue samples obtained from women with fetoplacental listeriosis. The results raised the possibility that L. monocytogenes crosses the maternofetal barrier th...

Outer membrane of Gram-negative bacteria is a permeability barrier to many antibacterial agents, including the glycopeptide antibiotics such as vancomycin hydrochloride and as a result these antibiotics are ineffective against Gram negative bacteria. Different strategies have been described to overcome such limitation, including application of nanoparticles, as was shown in our previous studies...

Journal: :Gut 2006
V Lorenzo-Zúñiga C M Rodríguez-Ortigosa R Bartolí M-L Martínez-Chantar L Martínez-Peralta A Pardo I Ojanguren J Quiroga R Planas J Prieto

BACKGROUND AND AIMS In liver cirrhosis, disruption of the intestinal barrier facilitates bacterial translocation and spontaneous bacterial peritonitis. Insulin-like growth factor I (IGF-I) is an anabolic hormone synthesised by hepatocytes that displays hepatoprotective activities and trophic effects on the intestine. The aim of this study was to investigate the effect of IGF-I on intestinal bar...

Journal: :The Journal of Experimental Medicine 1989
E I Tuomanen K Saukkonen S Sande C Cioffe S D Wright

We tested if specific inhibition of recruitment of leukocytes across the blood brain barrier from the vascular compartment to the cerebrospinal fluid (CSF) space reduced tissue damage and improved the outcome of infection in a rabbit model of experimental meningitis. The CD11/CD18 complex of receptors on leukocytes promotes adhesion of these cells to endothelia, a process required for egress of...

Journal: :International journal of biosciences 2022

Bacterial meningitis (BM) affects the central nervous system (CNS) and is a significant long-term sequela for 50% of survivors globally. Resource-poor areas have higher prevalence acute bacterial than resource-rich ones. The pathogenesis BM involves intricate pathways linked to survival proliferation in circulation, increased blood-brain barrier (BBB) permeability, oxidative […]

2016
Alexander S Zevin Irene Y Xie Kenzie Birse Kelly Arnold Laura Romas Garrett Westmacott Richard M Novak Stuart McCorrister Lyle R McKinnon Craig R Cohen Romel Mackelprang Jairam Lingappa Doug A Lauffenburger Nichole R Klatt Adam D Burgener

The mechanism(s) by which bacterial communities impact susceptibility to infectious diseases, such as HIV, and maintain female genital tract (FGT) health are poorly understood. Evaluation of FGT bacteria has predominantly been limited to studies of species abundance, but not bacterial function. We therefore sought to examine the relationship of bacterial community composition and function with ...

Journal: :American journal of physiology. Gastrointestinal and liver physiology 2009
V S Conlin X Wu C Nguyen C Dai B A Vallance A M J Buchan L Boyer K Jacobson

Attaching and effacing bacterial pathogens attach to the apical surface of epithelial cells and disrupt epithelial barrier function, increasing permeability and allowing luminal contents access to the underlying milieu. Previous in vitro studies demonstrated that the neuropeptide vasoactive intestinal peptide (VIP) regulates epithelial paracellular permeability, and the high concentrations and ...

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