The role of the low density lipoprotein receptor (LDLR) in the clearance of apo-B48-containing lipoproteins and the role of the LDLR-related protein (LRP) in the removal of apo-B100-containing lipoproteins have not been clearly defined. To address these issues, we characterized LDLR-deficient mice homozygous for an "apo-B48-only" allele, an "apo-B100-only" allele, or a wild-type apo-B allele (L...

Monoclonal antibodies (mAB) were raised to be used as probes to identify cytoplasmic components associated with intermediate filaments (IF). Four hybridomas (B27, B76, B78, and B100) secreting mAB were generated by fusing mouse myeloma cells with the spleen cells of mice immunized intraperitoneally with Triton-high salt insoluble materials from BHK-21 cells. This insoluble material consists mos...

Fossil fuels such as diesel are being gradually replaced by biodiesel, a renewable energy source, cheaper and less polluting. However, little is known about the toxic effects of this new energy source on aquatic organisms. Thus, we evaluated biochemical biomarkers related to oxidative stress in Nile tilapia (Oreochromis niloticus) after two and seven exposure days to diesel and pure biodiesel (...

BACKGROUND The microsomal triglyceride transfer protein (MTP) is involved in hepatic and intestinal apoB secretion. We studied the effect of the functional MTP-493G/T polymorphism on fasting and postprandial lipoproteins in patients with familial combined hyperlipidemia (FCH) before and after treatment with atorvastatin. METHODS Eight FCH heterozygote carriers of the rare -493T allele were co...

Objective—The risk of atherosclerosis in the setting of chylomicronemia has been a topic of debate. In this study, we examined susceptibility to atherosclerosis in Gpihbp1-deficient mice (Gpihbp1 / ), which manifest severe chylomicronemia as a result of defective lipolysis. Methods and Results—Gpihbp1 / mice on a chow diet have plasma triglyceride and cholesterol levels of 2812 209 and 319 27 m...

High performance thin layer chromatography (HPTLC) combined with on-spot detection and characterization via easy ambient sonic-spray ionization mass spectrometry (EASI-MS) is applied to the analysis of biodiesel (B100) and biodiesel-petrodiesel blends (BX). HPTLC provides chromatographic resolution of major components whereas EASI-MS allows on-spot characterization performed directly on the HPT...

Objectives: Dyslipidemia, a very common complication of diabetes mellitus (DM), is associated with life threatening complication like coronary artery disease (CAD). Apolipoprotein A-I and apo B100 are the protein components of high density lipoprotein (HDL-C) and low density lipoprotein (LDL-C) respectively. Apo B100/apo A-I ratio represents the balance between pro-atherogenic and antiatherogen...

BACKGROUND The simultaneous presence of chronic hepatitis B (CHB) and metabolic syndrome (MS) in the high-risk Roma community constitutes a high risk for liver cirrhosis and potentially hepatocellular carcinoma. This study aims to explore the relationship between MS and CHB. METHODS Data from the cross-sectional HepaMeta Study conducted in Slovakia in 2011 among Roma living in rural communiti...

Soybean biodiesel (B100) has been playing an important role in Brazilian energy matrix towards the national bio-based economy. Greenhouse gas (GHG) emissions is the most widely used indicator for assessing the environmental sustainability of biodiesels and received particular attention among decision makers in business and politics, as well as consumers. Former studies have been mainly focused ...

In the given article, results of tribological research chrome-gray cast iron coupling are presented, friction conditions between cylinder liner and compression segment being lubricated in various environments modeled: diesel (control), pure biodiesel B100 biodiesel-diesel B20 mixture. It was established that average values coefficient coupling, case using biofuels B20, as lubricating material, ...