A terrain M is the graph of a continuous bivariate function. We assume that M is represented as a triangulated surface with N vertices. A contour (or isoline) of M is a connected component of a level set of M. Generically, each contour is a closed polygonal curve; at “critical” levels these curves may touch each other or collapse to points. We present I/O-efficient algorithms for the following ...

The metabolic regulation of blood flow is central to guaranteeing an adequate supply of blood to the tissues and microvascular network stability. It is assumed that vascular reactions to local oxygenation match blood supply to tissue demand via negative-feedback regulation. Low oxygen (O 2 ) levels evoke vasodilatation, and thus an increase of blood flow and oxygen supply, by increasing (decrea...

The metabolic regulation of blood flow is central to guaranteeing an adequate supply of blood to the tissues and microvascular network stability. It is assumed that vascular reactions to local oxygenation match blood supply to tissue demand via negative-feedback regulation. Low oxygen (O 2 ) levels evoke vasodilatation, and thus an increase of blood flow and oxygen supply, by increasing (decrea...

Time-resolved decays of fluorescence anisotropy were obtained from frequency-domain measurements of the phase angle difference between the parallel and perpendicular components of the polarized emission and the ratio of the modulated amplitudes. These data were measured at modulation frequencies ranging from 1 to 200 MHz. To demonstrate the general applicability of this method, we describe the ...

Abstract Introduction Insomnia is the most prevalent sleep disorder, with 10% of adults meeting criteria for a chronic insomnia disorder (CID). Cognitive-behavioral therapy (CBT-I) first-line recommended treatment given strong evidence supporting its efficacy in short-term and mid-term. Less known about effectiveness CBT-I routine clinical practice on patient-reported outcomes beyond 3y post-tr...

In this note we show the existence of weak ε-nets of size O (1/ε log log (1/ε)) for point sets and axis-parallel boxes in R. Our analysis uses a non-trivial variant for the recent technique of Aronov et al. [AES09] that yields (strong) ε-nets, whose size have the above asymptotic bound, for d = 2, 3. Work on this paper has been supported by NSF under grants CNS-05-40347, CFF-06-35000, and DEB-0...

Centre-related factors are known to influence the outcomes of patients on peritoneal dialysis (PD) and explain some variability in that cannot be explained solely by patient-related factors. It is unclear if PD nurse-patient ratios nurses’ training impacts patients' PD. We aimed ascertain individual units across Australia evaluate for any association with unit-specific PD-associated peritonitis...