Objective: To investigate the effects of avocado (A)/soybean (S) unsaponifiables on the metabolism of human osteoarthritic (OA) chondrocytes cultured in alginate beads over 12 days. Methods: Enzymatically isolated OA chondrocytes were cultured in alginate beads in a well defined culture medium for 12 days, in the presence or not of 10 10 M interleukin 1ß (IL-1ß). DNA content was measured using ...

objective: the aim of this study was to evaluate the clinical efficacy of an herbal medicine, piascledine, on the treatment of chronic periodontitis. materials and methods: twenty-four patients with chronic periodontitis participated in this interventional case control investigation. after initial screening the subjects were divided into case and control groups. clinical measurements including ...

A simple gas-liquid chromatographic method has been developed for the measurement of cholesterol and some plant sterols, such as campesterol, ~-sitosterol and avenasterol, in pasta products. Samples were saponified, without prior extraction of lipids, and the concentrated unsaponifiables analysed directly by gas liquid chromatography. The results were evaluated statistically, and they showed th...

Avocado/soy unsaponifiable (ASU) components are reported to have a chondroprotective effect by virtue of anti-inflammatory and proanabolic effects on articular chondrocytes. The identity of the active component(s) remains unknown. In general, sterols, the major component of unsaponifiable plant material have been demonstrated to be anti-inflammatory in vitro and in animal models. These studies ...