نتایج جستجو برای: autocatalytic model
تعداد نتایج: 2105579 فیلتر نتایج به سال:
In small volumes, the kinetics of filamentous protein self-assembly is expected to show significant variability, arising from intrinsic molecular noise. This is not accounted for in existing deterministic models. We introduce a simple stochastic model including nucleation and autocatalytic growth via elongation and fragmentation, which allows us to predict the effects of molecular noise on the ...
This paper develops some basic principles to study autocatalytic networks and exploit their structural properties in order to characterize their inherent fundamental limits and tradeoffs. In a dynamical system with autocatalytic structure, the system’s output is necessary to catalyze its own production. We consider a simplified model of Glycolysis pathway as our motivating application. First, t...
The Gillespie Algorithm is used to simulate a prion model so that the kinetics of the prions may be observed. The model is purely autocatalytic, that is, there is no fusion or fission of the infectious units. There is only conversion of PrP C into prions through a mechanism comprised of attaching PrP C to a PrP Sc p-mer, domain swapping, and splitting. It is well known that any model of an infe...
There are deep underlying similarities between Rosen’s (M,R) systems as a definition of life and the RAF sets (Reflexive Autocatalytic systems generated by a Food source) introduced by Hordijk and Steel as a way of analyzing autocatalytic sets of reactions. Using RAF concepts we have systematically explored the set of possible small idealized metabolic networks, searching for instances of (M,R)...
This paper presents new results from a detailed study of the structure of autocatalytic sets. We show how autocatalytic sets can be decomposed into smaller autocatalytic subsets, and how these subsets can be identified and classified. We then argue how this has important consequences for the evolvability, enablement, and emergence of autocatalytic sets. We end with some speculation on how all t...
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