نتایج جستجو برای: auto inhibition

تعداد نتایج: 354924  

E. Nikkhah, M. Khayami R. Heidari

Antioxidant activity of Berry (Morus alba var. nigra) was investigated. For superoxide anion radical assay, the superoxide anion radicals were generated by a pyrogallol auto oxidation system, Nitric oxide radical inhibition by the use of Griess Illosvoy reaction and reducing power was determined according to the Oyaizu method. At least this sample was represented a potential antioxidant capacit...

Journal: :The Journal of biological chemistry 2007
Marielle E Yohe Kent L Rossman Olivia S Gardner Antoine E Karnoub Jason T Snyder Svetlana Gershburg Lee M Graves Channing J Der John Sondek

Dbl-related oncoproteins are guanine nucleotide exchange factors specific for Rho-family GTPases and typically possess tandem Dbl homology (DH) and pleckstrin homology domains that act in concert to catalyze exchange. Because the ability of many Dbl-family proteins to catalyze exchange is constitutively activated by truncations N-terminal to their DH domains, it has been proposed that the activ...

Journal: :physiology and pharmacology 0
irfan ahmed sheikh department of biosciences, barkatullah university, bhopal (mp - 462 026), india muhammad mubashshir department of medical lab & tech., al-falah university, faridabad (haryana - 121 004), india safia sumoona department of biosciences, barkatullah university, bhopal (mp - 462 026), india mohd ovais department of biosciences, barkatullah university, bhopal (mp - 462 026), india

introduction: effects of melatonin (mt) were comparatively examined on melanophores of isolated skin in adults and tadpole’s tailfin of a frog rana cyanophlyctis. mt is generally considered as a potent melanophores aggregating hormone besides regulating the sleep wake cycle in vertebrates. methods: melanophore size index (msi) was chosen as a recording parameter of the responses. concentration-...

Journal: :American journal of health promotion : AJHP 2007
Matthew A Coogan Karla H Karash Thomas Adler James Sallis

PURPOSE To examine the association of personal values, the built environment, and auto availability with walking for transportation. SETTING Participants were drawn from 11 U.S. metropolitan areas with good transit services. SUBJECTS 865 adults who had recently made or were contemplating making a residential move. MEASURES Respondents reported if walking was their primary mode for nine tr...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2011
Francisco J Quintero Juliana Martinez-Atienza Irene Villalta Xingyu Jiang Woe-Yeon Kim Zhair Ali Hiroaki Fujii Imelda Mendoza Dae-Jin Yun Jian-Kang Zhu Jose M Pardo

The plasma membrane sodium/proton exchanger Salt-Overly-Sensitive 1 (SOS1) is a critical salt tolerance determinant in plants. The SOS2-SOS3 calcium-dependent protein kinase complex up-regulates SOS1 activity, but the mechanistic details of this crucial event remain unresolved. Here we show that SOS1 is maintained in a resting state by a C-terminal auto-inhibitory domain that is the target of S...

Journal: :The Journal of biological chemistry 2010
Aurelie Gresset Stephanie N Hicks T Kendall Harden John Sondek

The lipase activity of most phospholipases C (PLCs) is basally repressed by a highly degenerate and mostly disordered X/Y linker inserted within the catalytic domain. Release of this auto-inhibition is driven by electrostatic repulsion between the plasma membrane and the electronegative X/Y linker. In contrast, PLC-γ isozymes (PLC-γ1 and -γ2) are structurally distinct from other PLCs because mu...

2015
Guan-Feng Wang Jiabing Ji Farid EI-Kasmi Jeffery L. Dangl Guri Johal Peter J. Balint-Kurti

Plant disease resistance is often mediated by nucleotide binding-leucine rich repeat (NLR) proteins which remain auto-inhibited until recognition of specific pathogen-derived molecules causes their activation, triggering a rapid, localized cell death called a hypersensitive response (HR). Three domains are recognized in one of the major classes of NLR proteins: a coiled-coil (CC), a nucleotide ...

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