The tissue polarity genes control the polarity of hairs, bristles and ommatidia in the adult epidermis of Drosophila. We report here the identification of a new tissue polarity gene named starry night (stan). Mutations in this essential gene alter the polarity of cuticular structures in all regions of the adult body. The detailed polarity phenotype of stan on the wing suggested that it is most ...

This paper uses data on more than 4000 captives ransomed from the Barbary corsairs to track the military power of the Ottoman Empire’s most powerful North African regency over time. Results suggest that as the seventeenth century advanced, Algerian-based corsairs found it increasingly difficult to capture “hard” targets. These results do not appear to be driven by changes in ransoming preferenc...

OBJECTIVE To examine whether intrapartum monitoring by means of automatic ST analysis (STAN) of fetal electrocardiography could reduce the rate of neonatal acidemia and the rate of operative intervention during labour, compared with monitoring by means of cardiotocography (CTG). DESIGN Randomised controlled trial. SETTING Labour ward in tertiary-level university hospital. SAMPLE A total o...

OBJECTIVE Fetal peripartum surveillance with ST analysis of fetal electrocardiogram (STAN) alone or in combination with fetal blood sampling (FBS) is a worldwide debate. STAN monitoring without FBS support was implemented in 2000 in the authors' department when it took part in a European multicentre project. The aim of this study was to evaluate neonatal outcomes associated with peripartum STAN...

Lipoprotein glomerulopathy (LPG) is a rare glomerulopathy caused by lipoprotein thrombi. In almost all cases of LPG, several apolipoprotein (apo) E mutations were reported. Here, we present a case of LPG caused by a novel mutation that we named ApoE2 Kurashiki, which substitutes arginine with proline at apoE codon 158. ApoE2 polymorphism is well known for its relationship to type III hyperlipop...

Research briefs: Gravitational Microlensing and the Search for Dark Matter: A Personal View, Bohdan Paczynski . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 Laboratory Gravity: The G Mystery and Intrinsic Spin Experiments, Riley Newman . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11 LIGO Project update, Stan Whitcomb . . . . . . . . . . . ...

OBJECTIVE To study interobserver agreement in the assessment of intrapartum automated fetal electrocardiogram ST interval analysis (STAN). DESIGN Observational study. SETTING Labor ward in tertiary level university hospital. Sample. Two hundred (140 reassuring and 60 non-reassuring) STAN recordings on non-selected women with singleton, vertex, term pregnancies were selected from our archive...

The paper profited significantly from the discussions there. Furthermore, we acknowledge the sub stan-tia l input provided thereafter from Patrick Kenis.

OBJECTIVE To assess the impact of introduction of the STAN monitoring system. STUDY DESIGN Prospective observational study. SETTING Tertiary referral labour ward, St George's Hospital, London. POPULATION High-risk term pregnancies. METHODS We report all consecutive cases of intrapartum monitoring using the STAN S 21 fetal heart monitor. Cases with adverse neonatal outcome were evaluated...