We examined the inhibitory effect of polyphenol-rich aqueous extract from the bark of Acacia mearnsii (PrA) on itching associated with atopic dermatitis (AD). HR-1 mice were fed a normal diet, special diet (AD group), or special diet containing 3% PrA (PrA group) for 6 weeks. In the AD group, itching frequency and transepidermal water loss increased compared to the control group. In the PrA gro...

Atopic dermatitis is one of the commonest childhood diseases. Large variations in the prevalence of the disease have been observed in different studies. This variation in the prevalence may be not only from genetic and environmental factors but also from methodology of estimating prevalence of the disease. In this study, Hanifin and UKWP criteria have been used in determining prevalence of the ...

Background and aim: Atopic dermatitis (AD) is a chronic relapsing skin disease that commonly begins during infancy and early childhood. Research studies refers to a relationship between exacerbation of atopic dermatitis and exposure to house dust mite (HDM), but the role of HDM in the pathogenesis of AD is controversial. The objecitve of this study was to assess the correlation of density...

introduction: atopic dermatitis (ad) is a multifactorial chronic and inflammatory disease present all over the world. only a few epidemiologic studies on ad have been carried out in the eastern world, while most of the published papers belong to western countries. to determine prevalence of ad in 7-11 year-old school children in ahwaz as there has been no previous study in this region. methods:...

The aim of this study was to evaluate the effect of underwear made of ethylene vinyl alcohol (EVOH) fiber in children with atopic dermatitis (AD). Twenty-one AD children (11 EVOH group and 10 control group) were studied for 4 weeks. Their AD severity based on the Scoring Atopic Dermatitis (SCORAD) score and physiological functions were assessed. The objective SCORAD significantly decreased in b...

Atopic Dermatitis (AD) is a common inflammatory, pruritic skin disorder. It is a chronic disease with often relapse. Several factors including genetic predisposition, allergies to specific foods, irritant chemicals, and aeroallergens are thought to be the cause of AD. Diagnosis is difficult, and often occurs after ruling out other disorders with a clinical presentation resembling atopic dermati...

AD: atopic dermatitis IL: interleukin Th: T helper cell INTRODUCTION Moderate-to-severe atopic dermatitis (AD) often requires systemic treatments with immunomodulatory drugs. Unfortunately, systemic agents currently used for AD have extensive side effects, and many patients experience suboptimal therapeutic responses. Additionally, many of these treatments, such as cyclosporine A, can only be u...

Atopic dermatitis (AD) is often the initial step in the "atopic march," given that more than half of AD patients with moderate to severe AD develop asthma later in life. Both AD and asthma share a similar "atopy" phenotype that includes T helper type 2 inflammation with eosinophilia and hyper-IgE immunoglobulinemia, but the molecular mechanisms underlying the "atopic march" remain elusive. In t...

atopy can be defined as the genetically determined risk to develop allergic disease. avoidance of one specific allergen may decrease the risk for sensitization against this allergen, but it will not affect atopy. our aim was to investigate if exclusive breast-feeding is associated with atopic dermatitis during the first 5 years of life. data on 200 children were taken from parental-administered...