Atherosclerosis has serious role in coronary arteries disease,so it is important to establish effective strategies for prevention or even treatment of atherosclerosis. Adiponectin, as one of the most abundant adipokines, has insulin sensitivity, anti-inflammatory and anti-atherogenic properties. Disturbed adiponectin actions through its receptor, (AdipoR1 and AdipoR2) may be involved in atheros...

Atherosclerosis has been defined as an inflammatory disease. Three decades of research have pointed to a pivotal role interleukin 6 for many aspects cardiovascular disease, not the least which is atherosclerosis. In this review, experimental and clinical studies are reported on timeline, exploring mechanisms possible explanations that form basis current knowledge. Some successful trials were pr...

The search for genes related to the cause of common complex disorders such as cardiovascular disease has been frustrating, partly because of the many factors known to contribute to cardiovascular disease and the potential "distance" of cardiovascular disease as a phenotype from genes and gene products. Linkage and association studies for phenotypes more proximal in the pathway from DNA sequence...

background: hemodialysis patients are at greater risk of cardiovascular disease. higher than expected cardiovascular morbidity and mortality in this population has been attributed to dislipidemia as well as inflammation. the causes of inflammation in hemodialysis patients are multifactorial. several markers were used for the detection of inflammatory reaction in patients with chronic renal dise...