Members of the Oct family of transcription factors specifically interact with the octamer motif, ATGC-AAAT, a regulatory element important for tissue- and cell-specific transcription as well as for the expression of housekeeping genes. Except for Oct-1, all Oct factors are expressed in a temporally and spatially restricted mode during murine development and their number varies in a given cell t...

The presence of restriction enzymes in bacterial cells has been predicted by either classical phage restriction-modification (R-M) tests, direct in vitro enzyme assays or more recently from bacterial genome sequence analysis. We have applied phage R-M test principles to the transformation of plasmid DNA and established a plasmid R-M test. To validate this test, six plasmids that contain BamHI f...

n-tuple power law widely exists in language, computer program code, DNA and music. After a vast amount of Zipf analyses of n-tuple power law from empirical data, we propose a model to explain the n-tuple power law feature existed in these information translational carriers. Our model is a preferential selection approach inspired by Simon’s model which explained scaling law of single symbol in a...

Recently, polymorphisms in macrophage inhibitory cytokine-1 (MIC1) and interleukin 1 receptor antagonist (IL1RN) were identified to be associated with prostate cancer risk (1-3). MIC-1 is a divergent member of the transforming growth factor-h superfamily of cytokines. In the Cancer Prostate in Sweden study, the nonsynonymous MIC1 H6D polymorphism was associated with a lowered risk of prostate c...

The future 100 TeV FCC-hh hadron collider will give access to rare but clean final states which are out of reach the HL-LHC. One such process is $Zh$ production channel in $(\nu\bar{\nu} / \ell^{+}\ell^{-})\gamma\gamma$ states. We study sensitivity this $\mathcal{O}_{\varphi q}^{(1)}$, q}^{(3)}$, u}$, and d}$ SMEFT operators, parametrize deviations $W$ $Z$ couplings quarks, or, equivalently, an...

Abstract Dew is a common form of water that deposits from saturated air on colder surfaces. Although presumably primordial Earth, its potential involvement in the origin life early replication has not been investigated detail. Here we report it can drive first stages Darwinian evolution for DNA and RNA, by periodically denaturing their structures at low temperatures second promoting long strand...

The W mass is a crucial parameter in the Standard Model (SM) of particle physics, providing constraints on the mass of the Higgs boson as well as on new physics models via quantum loop corrections. On the other hand, any deviation of the triple gauge boson couplings (TGC) from their values predicted by the SM would be also an indication for new physics. We present recent measurements on W boson...

The context sequence motif surrounding the ATG initiation codon influences mRNA translation efficiency and affects protein production; however, the optimal sequence differs among species. To determine the optimal sequence for production of recombinant proteins in a transgenic silkworm, we compared 14-nucleotide context motifs around the ATG (ATG-context) in 50 silkworm genes and found the follo...