Fractional anisotropy (FA) threshold is commonly used to perform diffusion MRI tractography. However, FA threshold may be one aspect of tractography that needs additional scrutiny in accurately assessing pathways in immature, developing brains, as well as in adult brains. Using high-angular resolution diffusion MRI (HARDI) tractography without an FA threshold, we identified the arcuate fascicul...

For the World Wide Web, the Transmission Control Protocol (TCP) and the HyperText Transfer Protocol (HTTP) are two important protocols. However, interactions between these two protocols, combined with the bandwidth asymmetry of network access technologies such as ADSL, can lead to inefficient HTTP/TCP performance. This paper investigates the effects of bandwidth asymmetry on Ensemble-TCP, a pro...

BACKGROUND The characteristics of atrial electrograms associated with atrial fibrillation (AF) termination are controversial. We investigated the electrogram characteristics that indicate procedural AF termination during continuous complex fractionated electrogram ablation. METHODS AND RESULTS Fifty-two consecutive patients with persistent AF (47 men; aged 54 ± 9 years), who underwent electro...

The development of the heart is a complex process during which different cell types progressively contribute to shape a four-chambered pumping organ. Over the last decades, our understanding of the specification and transcriptional regulation of cardiac development has been greatly augmented as has our understanding of the functional bases of cardiac electrophysiology during embryogenesis. The ...

The left atrium (LA) can change in size and shape due to atrial fibrillation (AF)-induced remodeling. These alterations can be linked to poorer outcomes of AF ablation. In this study, we propose a novel comprehensive computational analysis of LA anatomy to identify what features of LA shape can optimally predict post-ablation AF recurrence. To this end, we construct smooth 3D geometrical models...

Asymmetric magnetization reversal is an unusual phenomenon in antiferromagnet/ferromagnet (AF/FM) exchange biased bilayers. We investigated this phenomenon in a simple model system experimentally and by simulation assuming inhomogeneously distributed interfacial AF moments. The results suggest that the observed asymmetry originates from the intrinsic broken symmetry of the system, which results...

Despite the fact that as many as 25% of the children diagnosed with autism spectrum disorders are nonverbal, surprisingly little research has been conducted on this population. In particular, the mechanisms that underlie their absence of speech remain unknown. Using diffusion tensor imaging, we compared the structure of a language-related white matter tract (the arcuate fasciculus, AF) in five ...

AF is often treated by ablation to isolate the pulmonary veins where ectopic pacemaker activity or reentry may initiate AF. The relationship of gene expression and histology in vein unknown. To identify sections regions be indicative pathogenesis. Human (PV) sleeve tissues form ostia left atrium were obtained from 8 unused lung heart transplant donors a protocol approved Cleveland Clinic IRB. A...