conclusions our underlying hypothesis is that recapitulating the three-dimensional early embryonic structure, in order to reproduce better in vitro the three-dimensional morphogenetic-like re-arrangements, would improve cells differentiation, when in vivo transplanted; moreover, it could be used as a simplified cancer disease model and reliable drug evaluation method as well. results the proces...

conclusions the lack of difference between adma levels in patients with pa and eh suggests that endothelial dysfunction is more likely related to hypertension per se than to the specific etiology of elevated blood pressure. results patients with pa had significantly higher concentrations of adma than healthy controls (0.488 ± 0.085 vs. 0.433 ± 0.053 μmol/l, p = 0.027). no difference was found i...

RATIONALE Cardiac progenitor cells (CPCs) in the adult heart are used for cell-based treatment of myocardial damage, but factors determining stemness, self-renewal, and lineage commitment are poorly understood. Immortal DNA strands inherited through asymmetric chromatid segregation correlate with self-renewal of adult stem cells, but the capacity of CPCs for asymmetric segregation to retain imm...

Rationale: Cardiac progenitor cells (CPCs) in the adult heart are used for cell-based treatment of myocardial damage, but factors determining stemness, self-renewal, and lineage commitment are poorly understood. Immortal DNA strands inherited through asymmetric chromatid segregation correlate with self-renewal of adult stem cells, but the capacity of CPCs for asymmetric segregation to retain im...

abstract background: increase in nitric oxide (no) concentration accompanied by alteration in peritoneal immune defense reactions is involved in the pathogenesis of endometriosis. asymmetric dimethylarginine is an endogenous competitive inhibitor of no synthase. this study was designed to compare no metabolite (nitrite), asymmetric dimethylarginine, and estradiol concentrations in serum and per...

The main criterion in investment decisions is to maximize the investors utility. Traditional capital asset pricing models cannot be used when asset returns do not follow a normal distribution. For this reason, we use capital asset pricing model with independent and identically asymmetric power distributed (CAPM-IIAPD) and capital asset pricing model with asymmetric independent and identically a...