background and objectives: angiogenesis is essential for tumor survival. inhibiting angiogenesis could be a mechanism for hindering tumor development. numerous studies have now been focused on agiogenesis inhibitors and many of such studies have targeted plant materials. in the present study, crocus pallasii subsp. haussknechtii has been evaluated for anti-angiogenesis properties. methods: anti...

background and objectives: cancer is a public health problem all over the world. herbal medicines have a vital role in the prevention and treatment of cancer and large numbers of plants and their isolated constituents have shown potential anticancer activity. methods: twenty seven medicinal plants from southern iran provinces have been extracted with methanol and screened for their cytotoxic ac...

it has been reported that several members of convolvulaceae family such as convolvulus arvensis possess cytotoxic activity on some tumor cell lines. proteoglycan mixture, the water extract of c. arvensis with high molecular weight, has potent anti-angiogenesis and stimulating effects. in this study, arial parts of c. arvensis were collected and identified, and the cytotoxic effects of chlorofor...

background: although pentavalent antimony compounds are used as antileish-manial drugs but they are associated with limitations and several adverse complica-tions. therefore, always effort to find a new and effective treatment is desired. in this study, the effect of zno nanoparticles with mean particle size of 20 nanome-ters (nm) on leishmania major promastigotes and amastigotes was evaluated....

iran has 1260 km of coastline that borders the persian gulf and the oman sea in the northwest indian ocean. marine algae are one of the natural resources in the marine ecosystem which produce a wide range of new secondary metabolites with various biological activities that play an important role in the pharmaceutical care. in this study the cytotoxic activity of 28 marine algae of chabahar coas...

the genus stachys belongs to lamiaceae family with about 300 species and worldwide distribution. in the present study, the cytotoxic activity of four fractions of different satchys species (s. byzatina c. koch., s. inflata benth., s. setifera ten. and s. persica gmel.), has been investigated against ht-29 (colon carcinoma), caco-2 (colorectal adenocarcinoma), t-47d (breast ductal carcinoma) and...

introduction: this study aimed to compare the cytotoxicity of mta fillapex, ah-26 and apatite root canal sealers at different times after mixing. methods and materials: in this in vitro study, mta fillapex, ah-26 and apatite root canal sealer were spilled uniformly by 40 µm mesh in a 96-well plate. then, human fetal foreskin fibroblast cell line (hfff2) were added to each sealer cell culture me...

doxorubicin is a broad spectrum antibiotic used in the treatment of cancers. its dose dependent cardiotoxicity is the most serious side effect causing withdrawal of drug from hard chemotherapeutic regimen. statins are shown to be cytotoxic in concentrations higher than the effective doses for the treatment of hypercholesterolemia (40 mg/day). co-administration of statins and chemotherapeutic ag...