BACKGROUND Spontaneous bacterial peritonitis (SBP) is a serious complication in infants and children with chronic liver disease (CLD); however its diagnosis might be difficult. We aimed to study the feasibility of diagnosing SBP by routine ascitic fluid tapping in infants and children with CLD. METHODS We enrolled thirty infants and children with biopsy-proven CLD and ascites. Ascitic fluid w...

BACKGROUND Spontaneous bacterial peritonitis (SBP) has been typically described in hospitalized patients. There are little data on ascitic fluid infection in asymptomatic outpatients. The present study was aimed at determining the prevalence and risk factors for asymptomatic ascitic fluid infection among patients with liver cirrhosis attending an outpatient clinic. METHODS Between January 200...

The differential diagnosis of malignant ascites by traditional methods has been recently challenged. We had studied 100 cases of ascites (27 were of malignant ascites) to evaluate the role of ascitic fluid cholesterol levels as a marker in malignancy.100 cases of ascites were studied with regard to SAAG, ascitic fluid cholesterol levels and fluid cytology. FNAC & biopsy was performed wherever m...

Mongrel dogs with ascites created by inferior vena cava ligation were given cephalothin, cephaloridine, cefazolin, and cefamandole to evaluate the effect of protein binding and serum pharmacokinetics on the distribution of cephalosporins into ascitic fluid. Antibiotics were given intramuscularly (15 mg/kg) every 4 h for a total of eight doses. Antibiotic binding to dog serum and ascitic fluid w...

BACKGROUND AND AIM Spontaneous bacterial peritonitis (SBP) is a major complication of liver cirrhosis and accounts for significant mortality. Although oxygen free radicals and nitric oxide been implicated in the pathophysiology of liver cirrhosis, information on their role during the development of SBP is scarce. This study examined these active species in ascitic fluid from patients with SBP, ...

BACKGROUND Although elevated levels of lactoferrin provide a biomarker for inflammatory bowel diseases and colorectal cancer, the clinical significance of these elevated levels in ascitic fluid of patients with ascites caused by liver cirrhosis is limited. The aims of our study were to investigate the usefulness of ascitic fluid lactoferrin levels for the diagnosis of spontaneous bacterial peri...

Constriction of inferior vena cava above the diaphragm is used to produce experimental ascites in the dog. This type of experimental ascites drains the body protein reserves, reduces the level of circulating plasma proteins, and in effect is an internal plasmapheresis. As the ascitic fluid is withdrawn and the proteins measured, we observe a production of ascitic protein (80-90 gm. per week) co...

Spontaneous bacterial peritonitis (SBP) is a serious complication of advanced cirrhosis of the liver. Usually patients with SBP show symptoms such as fever, abdominal pain, worsening of renal function, hypotension or development of encephalopathy. The frequency of SBP among hospital-ised patients with advanced cirrhosis varies from 10% to 30% [1]. The mortality of SBP was 80% to 100% in the 196...

OBJECTIVE To determine the frequency and compare the culture yield of bacterial isolation by conventional and blood culture BACTEC bottle techniques in cirrhotic patients with spontaneous bacterial peritonitis (SBP). STUDY DESIGN Cross-sectional comparative study. PLACE AND DURATION OF STUDY Pathology Department, Bannu Medical College, Bannu, KPK, from January 2012 to December 2013. METHO...

Component levels of the fibrinolysin system in the plasma and ascitic fluid of Swiss mice bearing Ehrlich ascites tumor cells were determined during a 15-day tumor growth time phase. During tumor growth, the concentration of plasminogen in the ascitic fluid decreased inversely to the total packed cell volume. Free plasmin was not present in the ascitic fluid nor was there any measurable plasmin...