The brine shrimp (Artemia salina Leach) lethality bioassay offers an advantage in standardization and quality control of botanical products. This test is well correlated with antitumor activity (cytotoxicity) and can be used to monitor the activity of bioactive natural products. This paper reports the bioactivity of ethanol extracts from seven medicinal plants from the Northeast of Brazil (Acme...

BACKGROUND Artemia (Crustacea, Anostraca), also known as brine shrimp, are typical inhabitants of extreme environments. These hypersaline environments vary considerably in their physicochemical composition, and even their climatic conditions and elevation. Several thalassohaline (marine) environments along the Colombian Caribbean coast were surveyed in order to contribute to the knowledge of br...

Die Zusammensetzung und der Stoffwechsel der Carotinoide in adulten Exemplaren von Artemia salina wurden untersucht. Unabhängig von der Fütterung mit carotinoidfreier Hefe, mit an Oxicarotinoiden reicher Nahrung oder mit Oxocarotinoid-haltigen Algen lassen sich als Hauptpigmente Canthaxanthin (4.4'-Dioxo-/?-carotin) und Echinenon (4-Oxo-/?-carotin) nachweisen. Daneben wur­ den in einer Artemia-...

A protein-synthesizing system consisting of ribosomes and supernatant of undeveloped Artemia saline embryos is used for assay of mRNA translation and initiation factors. This system contains the components needed for chain elongation but has low levels of mRNA and initiation factors. Exogenous mRNA is readily translated upon addition of high-speed supernatant or ribosomal salt wash of developin...

Betulinic, ursolic and oleanolic acids isolated from the aerial parts of Eriope blanchetii (Lamiaceae) were subjected to different esterification reactions, yielding 12 C-3 position ester derivatives. All compounds were identified using spectroscopic techniques, such as IR, 1H-NMR and MS. The derivatives were further investigated for their antioxidant level, Artemia salina lethality and antimic...

Maculalactone A (1) constitutes a promising antifouling agent, inhibiting the formation of biofilms in marine and freshwater systems. In this study, we developed a new route, based on a late-stage formation of the butenolide core, leading to the total synthesis of maculalactone A (three steps, overall yield of 45%) and delivering material on a gram scale. In addition, analogues of the title com...

This study was designed to examine the nutritional composition, antioxidant activity and medium lethal concentration (LC50 value) of Tamarindus indica L. pulp and seed extracts in vitro. The extraction was set at 40◦C, 60◦C and 100◦C for 12 hours, 6 hours and 15 minutes respectively to determine the optimum extraction parameter whereas the anti-oxidant activity of the extracts was measured usin...

Two diterpene glycosides, ent-8(17)-labden-15-O-alpha-L-rhamnoside and ent-8(17)-labden-15-O-(3'-O-acetyl)-alpha-L-rhamnoside (new natural compounds) were isolated from propolis from El Salvador. The compounds showed significant antibacterial activity and moderate toxicity to Artemia salina nauplii. These are the first glycosides reported in bee glue.

The new 29-norcucurbitacin, desacetylfevicordin A (1), together with three known 29-norcucurbitacin derivatives (2-4) were isolated from seeds of the Indonesian medicinal plant, Phaleria macrocarpa (Scheff.) Boerl. The structures of 1-4 were elucidated on the basis of spectroscopic analyses and chemical transformation. These compounds exhibited toxicity against the brine shrimp (Artemia salina).

Red betel (Piper crocatum) is a plant that often used as medicine. belongs to the Piperaceae family, grows vines with heart-shaped leaves and stems, which grow alternately from stem appearance of are silvery red shiny when exposed sunlight. contains flavonoid compounds, alkaloids, tannins, phenolic compounds essential oils. The results showed ethanol extract leaf active such flavonoids phenolic...