1. Tambourgi DV, Morgan BP, De Andrade RMG, et al. Loxosceles intermedia spider envenomation induces activation of an endogenous metalloproteinase, resulting in cleavage of glycophorins from the erythrocyte surface and facilitating complement-mediated lysis. Blood. 2000;95:683-691. 2. Wasserman GS, Anderson PC. Loxoscelism and necrotic arachnidism. J Toxicol Clin Toxicol. 1983-1984;21:451-472. ...

INTRODUCTION This retrospective study shows the profile of arachnidism, ophidism, and scorpionism in the Ouro Preto Municipality, Brazil, from January 2007 to December 2013. METHODS The data were gathered from forms of the Epidemiological Surveillance Sector of the town's Health's Municipal Secretary. RESULTS Of the 412 envenomations, 308 were caused by spiders, 78 by scorpions, and 26 by s...

Knowledge of spider bites in Central Europe derives mainly from anecdotal case presentations; therefore we aimed to collect cases systematically. From June 2011 to November 2012 we prospectively collected 17 cases of alleged spider bites, and together with two spontaneous notifications later on, our database totaled 19 cases. Among them, eight cases could be verified. The causative species were...

N Engl J Med 2005;352:700-7. Copyright © 2005 Massachusetts Medical Society. utaneous injury caused by spider venom has been recognized by physicians in the United States only since the late 1950s, with recluse spiders (genus loxosceles) most frequently implicated. During the past five decades, the growing popular belief that spiders cause many cases of skin necrosis in the United States has re...

OBJECTIVE Bites from the brown recluse spider and other arachnids from the genus Loxosceles frequently induce necrotic skin lesions that can be recalcitrant to treatment and disfiguring. The authors used a rabbit model of dermonecrotic arachnidism to address the therapeutic efficacy of intradermal (id) polyclonal anti-Loxosceles Fab fragments (alphaLoxd Fab) raised against Loxosceles deserta sp...

BACKGROUND This review provides the physician with a clinical approach to the diagnosis and management of spider bites. It examines the recent literature concerning management of bites causing dermonecrosis, secondary infection, neuromuscular damage, and allergic reactions. METHODS Using the key words "spider bites," "brown recluse spider bites," "necrotic arachnidism," "black widow spider bi...