Ultraviolet radiation (UVR) is generally considered a primary tumorigenic agent. While UVR exposure has been studied, especially at the skin level, impact of UV on internal tissues and its effect appearance development tumors not yet fully examined. Although there are maximum limits for external tissues, other such as oral tissue, can be exposed to well. Over course diagnosis treatment, cells m...

Abstract Background Colorectal cancer (CRC), with a growing incidence trend worldwide, is resistant to apoptosis and has uncontrolled proliferation. It recently reported that probiotic microorganisms exert anticancer effects. The genus Bifidobacterium , one of the dominant bacterial populations in gastrointestinal tract, received increasing attention because widespread interest using it as heal...

Background: Disruption in spermatogenesis and infertility occurred after local testicular heating. In this study in addition to evaluation the long term effects of experimental bilateral and unilateral cryptorchidism on sperm parameters and structure of mouse testis, the genes that involved in programmed cell death after cryptorchidism and treatment methods of decreasing the germ cells in semin...

background: nowadays, oocytes and embryos vitrification has become a routine technique. based on clinical judgment, re-vitrification maybe required. but little is known about re-vitrification impact on genes expression. objective: the impact of re-vitrification on apoptotic and implanting genes, bax, bcl-2 and erbb4, at compaction stage embryos were evaluated in this study. materials and method...

objective(s):  being secreted by the pineal gland, melatonin induces cell proliferation in normal cells and induced apoptosis in cancer cells. the purpose of this study was to investigate effects of melatonin on main components and the expression of apoptotic genes in vitrified-thawed testicular germ cells of 6- day–old mice.  materials and methods: testes of neonate balb/c mice were vitrified-...

Okra (A.esculentus) is an antidiabetic plant that it's beneficial effects on ovarian dysfunction in diabetes condition has not been clarified. The present study was designed to examine the effect of Okra powder on serum oxidant/antioxidant status, ovarian structure and expression of apoptotic/antiapoptotic related genes in ovary of experimentally induced high fat diet diabetic rats. Diabetes wa...

 Objective(s):  Being secreted by the pineal gland, melatonin induces cell proliferation in normal cells and induced apoptosis in cancer cells. The purpose of this study was to investigate effects of melatonin on main components and the expression of apoptotic genes in vitrified-thawed testicular germ cells of 6- day–old mice.  Materials and Methods: Testes of neonate Balb/c mice were vitrifie...

Background: Colon cancer is one of the most diagnosed cancers in modern world. Chemotherapy relevant treatments for colon cancer, but this method treatment has severe and sometimes irreversible side effects. Therefore, alternative with fewer effects are highly considered. Natural herbal medicine been proven to be a great source these methods. Objectives: This study aimed investigate anti-prolif...