The association of thyroid disorders and thyroid-related treatments with psychiatric disorders is well known. What is not recognized yet is if antithyroid antibodies may cause psychosis in the absence of encephalopathy and thyroid dysfunction. I report here the cases of 4 patients who developed de-novo psychosis where I found they had high titers of antithyroid antibodies, both antithyroglobuli...

Dyshormonogenesis is an uncommon cause of congenital hypothyroidism. The most common abnormality is absent or insufficient thyroid peroxidase enzyme. Maternal intake of antithyroid drug can also lead to elevated thyroid stimulating hormone (TSH) in a neonate, albeit the scenario is temporary. We report one such interesting case where a clinically euthyroid neonate borne to a mother on antithyro...

hyperthyroidism is a common disease and one of the best methods for its treatment is radioiodine therapy. treatment with antithyroid drugs brings patients to euthyroidism before radioiodine therapy. antithyroid drugs should be discontinued before radioiodine therapy to increase thyroid uptake. the purpose of this study was to determine the optimal time of methimazole (mtz) discontinuation. one ...

OBJECTIVE To determine the effect of adjunctive antithyroid drugs on the risk of treatment failure, hypothyroidism, and adverse events after radioiodine treatment. DESIGN Meta-analysis. DATA SOURCES Electronic databases (Cochrane central register of controlled trials, Medline, Embase) searched to August 2006 and contact with experts. Review methods Three reviewers independently assessed tri...

BACKGROUND Optimal treatment of Graves' disease in paediatric patients is still a matter of controversy. Antithyroid drugs, radioiodine and thyroidectomy are the three therapeutic options available. AIM To report our experience of long-term medical treatment and outcome of paediatric Graves' disease. METHODS A 5-y-long medical protocol was implemented in 20 children and adolescents with Gra...

PURPOSE Graves disease is the most common cause of hyperthyroidism in children. Inorganic iodide has been used in combination with antithyroid drugs for more effective normalization of thyroid hormones in some cases of severe thyrotoxicosis. This study aimed to investigate clinical characteristics of childhood thyrotoxicosis and effectiveness of inorganic iodide in the early phase of treatment....

Destructive therapy for thyrotoxicosis frequently results in hypothyroidism, necessitating life-long treatment with thyroxine. Antithyroid drug therapy is followed by remission in a considerable proportion of patients and subsequent clinical hypothyroidism is rare. There thus seems to be a strong case for the use of antithyroid drugs as the initial treatment in most thyrotoxic patients under th...

ArticleCopyright : Jastrzębska; licensee BioMed Central Ltd.2015 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cit...

l Forty-one children and adolescents had thyroidectomies for Grave’s disease during an 8 yr period. Twenty patients became euthyroid within a short period after treatment with antithyroid drugs and had operations with minimal ditruption of their lives. Antithyroid drugs were administered to 20 patients for a longer period of time as a primary form of treatment for Grave’s disease. Complications...