Thyme is a herb with broncholytic und secretomotoric effects. Its activity on beta (2) receptors as a possible mechanism of action was demonstrated. Major components are thymol and carvacrol which are claimed to be responsible for its effects and, therefore, used for standardization in the German pharmacopoeia (0.03 % phenols calculated as thymol). Our aim was to investigate the impact of thymo...

Dracocephalum kotschyi is an essential oil containing plant found in Iran. In Iranian traditional medicine, D. kotschyi has been used as antispasmodic and analgesic but so far there is no pharmacological report about its antispasmodic activity. Therefore, the objective of this research was to study antispasmodic activity of the essential oil of D. kotschyi and two of its constituents namely lim...

BACKGROUND Myrsine africana is an herbaceous plant that is traditionally used as appetizer and carminative. Locally, it is used for the treatment of pulmonary tuberculosis, rheumatism and diarrhea by healers. The aims of the current study were to screen the crude methanol extract obtained from the aerial parts (leaves and stem) of M. africana, for antispasmodic actions on isolated tissues and f...

BACKGROUND We have previously reported that aerial parts of Tylophora hirsuta have antispasmodic profile. The current work is an attempt for isolation of pharmacologically active compound(s) that contribute for its antispasmodic activity. METHODS Preliminary phytochemical screening for crude methanol extract of Tylophora hirsuta (Th.Cr) is performed. Brine shrimp cytotoxicity of crude methano...

background: studies have shown that physalis alkekengi reduces implantation and induces antifertility in rat. in iranian traditional medicine it is believed that this plant has abortifacient and antifertility activities. objective: the goal of this study was to evaluate the effect of physalis alkekengi ripe fruit hydroalcoholic extract (pfe) on uterine contractility and its possible mechanism(s...

Problem statement: Persea cordata previously demonstrated antispasmodic action against two neurotransmitters. It is important confirm such action against other neurotransmitters. Approach: Present study described the antispasmodic activity of polar (EtOAc; n-BuOH) and non polar (nhexane; dichloromethane) fractions from the bark of Persea cordata, against guinea pig ileum contracted by 5-hydroxy...

Background The Psidium guajava, commonly known as the apple guava, has shown various biological activities related to its main constituents, such as flavonoids, carotenoids, terpenoids and phenolic compounds. Studies emphasize antispasmodic and antimicrobial properties in the treatment of diarrhea and dysentery. It also has hypoglycemiant, antioxidant, hepatoprotective, anti-allergic, antimicro...