BACKGROUND Gastroesophageal reflux disease (GERD) is a very prevalent disorder. Medical therapy improves symptoms in some but not all patients. Antireflux surgery is an excellent option for patients with persistent symptoms such as regurgitation, as well as for those with complete symptomatic resolution on acid-suppressive therapy. However, proper patient selection is critical to achieve excell...

Gastroesophageal reflux disease (GERD) is a common condition, and it is now generally recognized that modern medical therapy allows the physician to both heal the esophagitis and relieve the patients from troublesome symptoms such as heartburn, acid regurgitation and disabling chest pain. In addition, long-term therapy with potent acid inhibitory drugs can maintain these patients in clinical re...

Barrett's oesophagus is usually the result of severe reflux disease. Relief of reflux symptoms is the primary aim of treatment in patients with Barrett's oesophagus who do not have high-grade dysplasia. Some studies with medium-term (2-5 years) follow up show that antireflux surgery can provide good or excellent symptom control, with normal oesophageal acid exposure, in more than 90% of patient...

I would like to congratulate POSTMA and coworkers [1] for their placebo-controlled study on the effects of highdose omeprazole in patients with severe hyperresponsiveness and gastro-oesophageal reflux (GOR). Previously published reports of the effects of medical antireflux therapy in asthma have claimed effects ranging from improvements in lung function [2], asthma medication requirements, and ...

Gastroesophageal reflux disease (GERD) is a chronic condition requiring long-term treatment. Simple lifestyle modifications are the first methods employed by patients and, because of their low cost and simplicity, should be continued even when more potent therapies are initiated. Potent acid-suppressive therapy is currently the most important and successful medical therapy. Whereas healing of t...

INTRODUCTION AND OBJECTIVES antireflux surgery performed by an experienced surgeon is a maintenance option for patients with well-documented gastroesophageal reflux disease (GERD). Well-documented GERD is difficult to find, as GERD is a multifactorial disease in which the gastroesophageal junction, with its special anatomical and functional components, is important. In order to examine patient ...

The number of antireflux procedures performed for gastroesophageal reflux disease in the United States has increased in the past decade. In a sampling of US hospitals by the National Center for Health Statistics, the number of patients discharged with the International Classification of Disease (ICD-9-CM) classification 44.66 (“Other procedures for creation of esophagogastric sphincteric compet...

HYPOTHESIS Nissen fundoplication decreases the use of antireflux medications. DESIGN Retrospective cohort study using discharge abstract data and pharmacy data. SETTING Twelve regional Kaiser Permanente hospitals in southern California. PATIENTS Three hundred forty-two patients underwent Nissen fundoplication. INTERVENTION Nissen fundoplication. MAIN OUTCOME MEASURE Use of antireflux ...

BACKGROUND Endoscopic dilatation of esophageal strictures is a simple and safe procedure. AIM To analyze the long term outcome of conservative treatment for esophageal peptic stricture in patients with high surgical risk. PATIENTS AND METHODS Twenty consecutive patients, 13 male, whose mean age was 75.2 years, with a peptic stricture of the esophagus and high surgical risk were prospectivel...

Purpose: Prevalence of ureter and kidney duplication is roughly 1 per 125 people, and is associated with vesicoureteral reflux to lower pole in about 45% of cases. From antireflux surgical principles viewpoint, standard antireflux surgeries can be performed in these kidneys without releasing ureters from each other. We studied the results of Gil-Vernet antireflux surgery in 12 patients with dup...