Tinospora cordifolia is a deciduous climbing shrub described as ‘the one who protects the body against diseases’. It is one of the most versatile rejuvenating shrub also known as ’Giloya’ in Indian vernacular having many therapeutic applications. The pharmaceutical significance of this plant is mainly because of the leaves, barks and roots contain various bioactive compounds such as alkaloids, ...

Several antimicrobial and immunosuppressive effects have been attributed to the statins class of antihyperlipidemia drugs. Several studies have also indicated clinical benefits for the use of statins during the management of infections and sepsis. To assess whether the immunosuppressive effects of statins outweigh their antimicrobial effects during a fungal infection BALB/c mice were administer...

Spirogyra neglecta extract (SNE) has shown antihyperglycemia and antihyperlipidemia in type 2 diabetic mellitus (T2DM) rats. This study investigated the antioxidant and renoprotective effects of SNE in T2DM rats induced by high-fat diet with low-single dose streptozotocin. T2DM rats were fed daily with SNE (0.25, 0.5, and 1 g/kg BW) for 12 weeks. Renal morphology, malondialdehyde levels, qPCR, ...

Diabetes mellitus and cholesterol disorders are a lethal combination that places patients with diabetes 2-4 times more at risk for developing macrovascular microvascular complications. Risk factors Hyperlipidemia include age, sex, lifestyle, metabolic conditions affect the metabolism of plasma lipoproteins, insulin deficiency. This study aims to know determine demographic data (age, length stay...

This study was designed to evaluate the nutritional property of plantain-based dough meal, antioxidant activity and dyslipidemia-ameliorating potential in high-fat-induced rats. The flour blends, that is, plantain 70%, soy cake 30% (PSC); 65%, 30%, rice bran 5% (PSR); oat-bran (PSO); 60%, 5%, (PSRO); controls (100% Cerolina) were evaluated for proximate, amino acids, antioxidants, phenolic prof...

Background: The human inflammatory response plays an important role in the pathogenesis of atherosclerosis. An increase in the inflammatory responses notable by the levels of highly sensitive C-Reactive Protein (hsCRP) may be able to predict future cardiovascular events and the prognosis of post-acute coronary syndrome (ACS). In animal experiments and human in-vitro experiments, curcumin has be...

Objective: Dietary changes playmajor risk roles in oxidative stress andcardiovascular disease and modulate normal metabolic function. The present study was designed to investigate the ameliorative potential of different extracts of Hemidesmus indicus to experimental high-fat diet in wistar rats, and their possible mechanism of action.  Materials and Methods: Male wistar rats were divided into 6...