in this study, we investigated the antifungal effects of silver nanoparticles (ag-nps) on candida albicans (atcc 5027), saccharomyces cerevisiae (atcc 5027). investigating method by using minimum inhibitory concentration (mic) technique, some of drugs including amphotericin b, fluconazole and synthesized ag-nps have been obtained on the fungi and the changes on membrane reactions of yeasts have...

The echinocandins are large lipopeptide molecules that are inhibitors of beta-(1,3)-glucan synthesis, an action that damages fungal cell walls. In vitro and in vivo, the echinocandins are rapidly fungicidal against most Candida spp and fungistatic against Aspergillus spp. They are not active at clinically relevant concentrations against Zygomycetes, Cryptococcus neoformans, or Fusarium spp. No ...

In the United States, only 10 antifungal drugs are currently approved by the Food and Drug Administration (FDA) for the therapy of systemic fungal infections. As shown in table 1, these drugs belong to 3 principal classes: polyenes, pyrimidines, and azoles. Drugs that belong to other classes are also approved as topical antifungal drugs, but will not be considered further here. Although convent...

Similarities in fungal and animal cells make antifungal discovery efforts more difficult than those for other classes of antimicrobial drugs. Currently, there are only three major classes of antifungal drugs used for the treatment of systemic fungal diseases: polyenes, azoles, and echinocandins. Even in situations where the offending fungal organism is susceptible to the available drugs, treatm...

conclusions our findings indicate that resistance of c. albicans strains to azoles is more common in tokat, turkey. therefore, a strategy to control the inappropriate and widespread use of antifungal drugs is urgently needed. fungal culturing and antifungal susceptibility testing will be useful in patient management as well as resistance surveillance. materials and methods a total of 201 c. alb...

OBJECTIVE The aim of this study is to analyze the expenditures related to the use of antifungal drugs in patients with hematological malignancies. METHODS In this retrospective study, the expenditures related to use of antifungal drugs for treatment of invasive fungal infections in patients with hematological malignancies between November 2010 and November 2012 were analyzed. Expenditures of ...

In this study, we investigated the antifungal effects of silver nanoparticles (Ag-Nps) on Candida albicans (ATCC 5027), Saccharomyces cerevisiae (ATCC 5027). Investigating method by using Minimum Inhibitory Concentration (MIC) technique, some of drugs including Amphotericin B, Fluconazole and synthesized Ag-Nps have been obtained on the fungi and the changes on membrane reactions of yeasts have...

Search for naturally occurring compounds with antifungal activity has become quite intense due to the side effects of synthetic fungicides and the development of pathogens against such fungicides. Hence screening of various Siddha drugs for their antifungal activity against various strains of Candida albicans was considered worthwhile. Seven such Siddha drugs were screened for their antifungal ...

the present investigation was designed to formulate a natural tablet for the treatment of vaginal candidiasis in order to eliminate side effects that are caused by existing antifungal drugs. curcumin has promising antifungal activity in comparison with the existing azole antifungal drugs. bioadhesive curcumin vaginal tablets were prepared by direct compression with different ratios of biadhesiv...