Peptide hormone fibroblast growth factor-21 (FGF21) has insulin-mimetic properties. Dutchak et al. now suggest that FGF21 also acts in an autocrine fashion in adipocytes and is required to mediate effects of the PPARγ agonist class of antidiabetic drugs. Does this new property improve FGF21's fledgling clinical prospects or endorse a clinical resuscitation of PPARγ agonists?

Objects: The phytochemical screening and the antihyperglycemic impact of Pelargonium gravelens were performed to judge ethanol extract using alloxan-induced diabetic rats. Methods: Intragastric ethanolic amount level 220 mg/kg body weight given alloxan-encouraged male albino rats for four weeks. Diabetic control assumed equivalent quantity vehicle (Dimethylsulfoxide, DMSO) processed together wi...

Hibiscus rosasinensis flowers and leaves are available all over India and well known for its Antidiabetic property. In the present investigation aqueous extract and ethanolic extract of the flowers and leaves were made using soxhlet apparatus, water extract and maceration. The qualitative Phytochemical screening procedure was performed on each extract. Phytochemical study reveals that alkaloids...

Several medicinal plants are having hypoglycemic effects.[1], The World Health Organization has recommended that the assessment of traditional plant treatments for diabetes mellitus needs further investigation.[2], Several herbal medicines were described for the care of diabetes mellitus in ancient literature of Ayurveda in India. Many of the plants used as diet were reported to have antidiabet...

Cookies are the most popular bakery food consumed worldwide. The development of reduced-sugar soft cookies by using Finger Millet, Syzygium cumini L. (Jamun) and stevia extract was investigated. In addition to it, Buttermilk powder used as a bulking agent improve flavor, color texture along with other ingredients like flour, margarine, salt, sodium bicarbonate, water. creamery method production...

Pisum sativum (Family: Fabaceae), as known as green pea or garden pea, has long been important in diet due to its content of fiber, protein, starch, trace elements, and many phytochemical substances. It has been shown to possess antibacterial, antidiabetic, antifungal, anti-inflammatory, antihypercholesterolemia, and antioxidant activities and also shown anticancer property. Its nonnutritive bi...

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The study is designed to find out the biochemical basis of antidiabetic property of Symplocos cochinchinensis (SC), the main ingredient of 'Nisakathakadi' an Ayurvedic decoction for diabetes. Since diabetes is a multifactorial disease, ethanolic extract of the bark (SCE) and its fractions (hexane, dichloromethane, ethyl acetate and 90% ethanol) were evaluated by in vitro methods against multipl...