نتایج جستجو برای: antidepressant effect

تعداد نتایج: 1651793  

Journal: :Canadian journal of psychiatry. Revue canadienne de psychiatrie 1996
R Joffe S Sokolov D Streiner

OBJECTIVE To carry out a metaanalysis of antidepressant studies to calculate the effect sizes for antidepressant effect in depressive disorder. METHOD A metaanalysis of all antidepressant studies that included an active comparison drug as well as placebo was used to calculate the effect size. Articles were selected from a MEDLINE search for the period January 1966 to June 1995. Forty-nine stu...

Hajrasouliha, Shadi, Khakpour, Shahrzad ,

Background: Depression is a common psychological disorder and recent data confirm the increasing prevalence of this disease in the world. So far, antidepressant effects of many plants have been evaluated and some are accepted in the treatment of depression. The aim of the present study was to determine the antidepressant effect of Melissa Officinalis L. compared to fluoxetine. Materials and met...

2015
Kimberlee Downey Richard Jope

of a thesis at the University of Miami. Thesis supervised by Dr. Eleonore Beurel No. of pages in text. (58) Depression is a prevalent and debilitating mood disorder afflicting nearly one in five people in the United States. Current medications used for treatment of depression are inadequate because they have a delayed onset of therapeutic benefit, low efficacy, several side effects, and require...

A.H Jamshidi , M Kamalipour , S Akhondzadeh ,

Depression is a heterogeneous disorder often manifested with symptoms at the psychological, behavioral and physiological levels. Full remission is achieved in fewer than 50% of patients. Therefore, antidepressant or medications that achieve a better rate of success are urgently needed. Herbal medicine has a long and respected history, and holds a valuable place in the treatment of depression. A...

Objective(s): Studies indicate that major deficiency in the levels of monoaminergic transmitters is a reason for severe depression. On the other hand, it is shown that Carthamus tinctorius L. (CT) may improve neuropsychological injuries by regulation of the monoamine transporter action. Hence, the present study was undertaken to evaluate the involvement of monoaminergic systems in antidepressan...

2016
Hongkun Bao Pengzhan Ran Ming Zhu Lijuan Sun Bai Li Yangyang Hou Jun Nie Liping Shan Hongliang Li Shangyong Zheng Xiufeng Xu Chunjie Xiao Jing Du

Proteo-β-glucan from Maitake (PGM) is a strong immune regulator, and its receptor is called Dectin-1. Cumulative evidence suggests that AMPA receptors are important for the treatment of depression. Here, we report that PGM treatment leads to a significant antidepressant effect in the tail suspension test and forced swim test after sixty minutes of treatment in mice. After five consecutive days ...

2010
Shih-Jen Tsai Chen-Jee Hong Ying-Jay Liou

Evidence suggests that the down-regulation of the signaling pathway involving brain-derived neurotrophic factor (BDNF), a molecular element known to regulate neuronal plasticity and survival, plays an important role in the pathogenesis of major depression. The restoration of BDNF activity induced by antidepressant treatment has been implicated in the antidepressant therapeutic mechanism. Becaus...

Journal: :International Journal of Molecular Sciences 2020

باقری , کیوان, ضرغامی , مهران, فرزین , داوود,

Background and purpose: Depression is one of the most common psychiatric disorder that results in significant consequences in active population of the society. Ïn traditional manscripts there are many indications about the antidepressant effects of rose drops, but, sofar no scientific research has been done about this subject. The objective of present study is to determine the anti depr...

Journal: :Pharmaceutical Biology 2006

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