INTRODUCTION Recombinant hepatitis B vaccine was introduced in 1986 and has gradually replaced the plasma-derived hepatitis B vaccine. No published data are available on the immunogenicity of hepatitis B vaccines in Nigerians. The current study aimed to evaluate protective sero-conversion rates after vaccination with Shanvac-B rDNA hepatitis B vaccine in Nigerian subjects between January and Se...

Antibody titres were measured in patients with clinical syphilis, and the effect of treatment on the results of the Treponema pallidum immune adherence (TPIA) test is reported. In the Treponema pallidum haemagglutination (TPHA) test little change in antibody titre occurred after treatment while in the fluorescent treponemal antibody-absorbed (FTA-ABS) test only a slight decrease occurred. The d...

Complement fixing antibody in animals injected with heat killed tubercle bacilli in oil appears earlier in the lesion at the site of injection than in the blood serum. Complement fixing antibody in an extract prepared by suspending one part by weight of tissue from the local site in five parts of saline is in general in higher concentration than in the blood, for a period of approximately 3 wee...

BACKGROUND Mass vaccination of dogs is considered fundamental for national rabies control programmes in Sri Lanka, as dog is the main reservoir and transmitter of the disease. METHODS Dogs were followed to determine the sero-prevalence of antibodies to the rabies virus. Altogether 510 previously vaccinated and unvaccinated dogs with owners (domestic dogs) and dogs without owners (stray dogs) ...

ABO-incompatible live donor renal transplantation is a growing field. To avoid hyperacute rejection, pre-operative ABO antibody titres should be < 8. There are a number of therapeutic measures used to reduce these titres if they are high. This case report describes a patient initially found to have an extremely high anti-A IgG titre (512). The high titre results were concomitant with a positive...

OBJECTIVE The aim of this study was to establish a baseline titre for the population of Mumbai, Maharashtra, India. METHOD Four hundred healthy blood donors, attending blood donation camps, were screened using a survey questionnaire. Widal tube agglutination test was performed on the diluted sera (with 0.9% normal saline) of blood donors, with final dilution ranging from 1 : 40 to 1 : 320. ...

The sensitivity of HD antibody in cancer diagnosis/prognosis could be improved by detection of Immune Complex (IC) dissociated antibody. Combined evaluation of native HD and Immune Complex (IC) dissociated antibody was carried out. Presence and titre of these antibodies in cancer patients was investigated in serum samples obtained from 420 patients with various types of tumors. Results were com...