In medicinal chemistry nitrogen containing heterocycles are the most important compounds which show various biological activities. The cinnoline are nitrogenous derivatives and found to elicit many pharmacological actions like anti-hypertensive, antithrombotic, antihistamine, antileukemic, CNS activity, anti tumor, antibacterial and antisecretory activity. We planned to synthesis new series of ...

nepeta depauperata belongs to the lamiaceae family and is one the persian endemic plants which has not been investigated biologically. in the present paper we had focused on the assessment of the antibacterial and antifungal activities of the total methanolic extract and different sub-fraction of the flowering aerial parts of it. the antibacterial and antifungal activities were investigated by ...

This study was carried out with an objective to investigate the antibacterial and antifungal potential of leaves of Cordia macleodii and Leucas ciliata. Antibacterial activity of ethanolic extracts of the leaves was carried out against three Gram negative bacteria – Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa and two Gram positive bacteria – Bacillus Subtilis and Staphylo...

the root and flowers of butea monosperma (lam.) were extracted with methanol. extensive chromatographic separation and purification with the organic solvents was done. four phytochemicals were separated and their structures were established based on various spectroscopic techniques. isolated crude extract was subjected for antibacterial activity against gram-negative and gram-positive bacteria ...

Abstract: A series of N-[2-(8-metoxy-2H-chromen-2-one)ethyl] piperazinyl quinolones containing a carbonyl related functional groups (oxo or oxyimino) on the ethyl spacer of coumarin and piperazin rings was synthesized and studied for their antibacterial and antifungal activities . The synthesis of compounds (6a-6l) was achieved through the versatile and efficient synthetic route that involved r...

Abstract: A series of N-[2-(8-metoxy-2H-chromen-2-one)ethyl] piperazinyl quinolones containing a carbonyl related functional groups (oxo or oxyimino) on the ethyl spacer of coumarin and piperazin rings was synthesized and studied for their antibacterial and antifungal activities . The synthesis of compounds (6a-6l) was achieved through the versatile and efficient synthetic route that involved r...

introduction: natural products have been the most successful source of potential drug leads. one of them is lichens, which have been used since antiquity as natural sources of drugs. the aim of this study was to investigate the antibacterial and antifungal activity of different extracts of the iranian lichens in ilam province. methods: the aqueous, acetone, and methanol extracts of 6 lichen spe...

brown alga, turbinaria conoides was successively extracted with n-hexane, cyclohexane, methanol and ethanol:water (1:1). the extracts were evaluated for antibacterial and antifungal activities by disc diffusion method. minimal inhibitory concentration was determined for active extracts by broth dilution method. the antiviral activity and cytotoxicity of the extracts were tested in human embryon...

the antimicrobial efficacy of methanol and water extracts of seeds of the plant swietenia macrophylla (family: meliaceae) was evaluated against selected pathogenic bacterial strains (bacillus cereus mtcc 430, klebsiella penumoniae mtcc 109, pseudomonas aeruginosa mtcc 424, escherichia  coli mtcc 443, staphylococcus aureus mtcc 96, salmonella typhimurium mtcc 98, micrococcus luteus mtcc 106) and...