the aim of this study was assessing the adjuvant therapy of exercise on cytokines balance in mice with breast cancer tumor. twenty female balb/c mice were randomly assigned to experimental and control groups. after orientation in the environment, estrogen-receptor dependent breast cancer cells (mc4-l2) were injected to them and experimental group performed endurance training 5 day in week for 6...

Background: In this study, the effects of three structural analogues of adenosine upon proliferation of human tumor cells were investigated. Previous research showed a cytotoxic effect of adenosine via A3 receptor and A1 receptor and sometimes this effect was receptor independent. The researches showed a differential cytotoxic effect of adenosine and its A3 agonists on cancerous cells, while ot...

patients with malignancy are at higher risk of thrombotic complications due to the hypercoagulability state. our objective in this study was to assess the serum concentrations of homocysteine, anti phospholipid antibodies, and anti cardiolipin in patients with benign and malignant breast tumors and study the effect of chemotherapy on the serum levels of these markers. a case control study was c...

in this study a 3-factor, 3-level box-behnken design was used to prepare optimized docetaxel (dtx) loaded pegylated poly lactide-co-glycolide (peg-plga) nps with polymer concentration (x1), drug concentration (x2) and ratio of the organic to aqueous solvent (x3) as the independent variables and particle size (y1), poly dispersity index (pdi) (y2) and drug loading (y3) as the responses. the cyto...

Stimulator of interferon genes (STING) contributes to anti-tumor immunity by activating antigen-presenting cells and inducing mobilization tumor-specific T cells. A role for tumor-migrating neutrophils in the effect STING-activating therapy has not been defined. We used mouse tumor transplantation models assessing neutrophil migration into triggered intratumoral treatment with STING agonist, 2?...

introduction: shallot is a plant which belongs to alium and albale family , this is a native plant from iran which is self – grown in high zones. by regard to further use of medicine and plant’s product , use of herbal plants has on important nole in medical treatment and preventi of diseale. the purpose of this study is the photo chemistry properties and anti – bacterial effects of this plant....