in many acute leukemias, normal differentiation does not occur. however, in many cell lines derived from hematologic malignancies, differentiation or programmed cell death (apoptosis) can be induced by variety of agents including: vitamin analogs, demethylating agents, cyclic amp analogs and anti-proliferative agents. to the best of our knowledge there has been not any study specifically to ana...

The strong anti-proliferative properties of an original family gold(i) complexes were assessed (submicromolar range activity).

Background: Anti-angiogenic therapy is a crucial step in cancer treatment. The discovery of new anti-angiogenic compounds from marine organisms has become an attractive concept in anti-cancer therapy. Because little data correlated to the pro- and anti-angiogenic efficacies of Ophiuroidea, which include brittle star, the current study was designed to explore the anti-angiogenic potential of bri...

background and objectives: the aerial part extracts of eremostachys macrophylla  from labiatae family, which has been traditionally used in wound healing, snake bites, rheumatism and joint pains, were investigated for general toxicity, anti-proliferative, free radical scavenging and anti-bacterial effects.moreover, preliminary phytochemical investigations were carried out on the extracts. metho...

Background and objectives: The aerial parts of Artemisia marschalliana Sprengel as an indigenous species of genus Artemisia in the East Azerbaijan province of Iran, was subjected to phytochemical analysis, as well asanti-proliferative, free-radical-scavenging and anti-malarialactivities. Methods: The chemical composition of the essential oil o...