neuroinflammation is inflammation of the nervous tissue. it be initiated in response to infection, toxic metabolites, auto immunity, traumatic brain injury and variety of causes. exercise is a promising mechanism of prevention and treatment for disease characterized by neuroinflammation. the benefits of exercise and physical activity (pa) are well known and have effects on function of the centr...

burns are known as one of the most common forms of injury with devastating consequences. despite the discovery of several antiseptics, burn wound healing has still remained a challenge to modern medicine. herbal products seem to possess moderate efficacy with no or less toxicity and are less expensive compared to synthetic drugs. burn is a well-known disorder in iranian traditional medicine (it...

in the present study, anti-anaphylactic, anti-inflammatory and membrane stabilizing properties of a lupine alkaloid plumerianine (compound 1), isolated from the root bark of plumeria acutifolia poir were investigated in animal models. the anti-anaphylactic activity of compound 1 (10, 25 and 50 mg/kg) was studied by using models such as passive cutaneous anaphylaxis, passive paw anaphylaxis and ...

background: evidences show that aloe vera (a. vera), camellia sinensis, hibiscus sabdariffa and sophora alopecuroides may prevent gastric ulcer induced by non-steroidal anti-inflammatory drugs (nsaids). objective: to examine the protective potential of these plants against indomethacin-induced gastric ulcer in the rat. methods: saline, a. vera leaf gel powder and 70% alcoholic extracts of the o...

abstract background and purpose: paederus associated dermatitis has always been considered as a health problem in the northern of iran. since until now, the traditional method and some corticosteroids have been used in the treatment of paederus dermatitis (pd) and no comprehensive studies have been carried out on the new method of treatment. therefore, this study was aimed to compare the anti-i...

objective(s) aristolochia indica has been widely used in the traditional medicine for the treatment of a variety of diseases. in the present study different extracts of roots of a. indica were evaluated for their anti­inflammatory, antipruritic and mast cell stabilizing activity. materials and methods anti-inflammatory activity was performed by compound 48/80 induced rat paw edema model and ant...

background worldwide, the incidence of inflammatory bowel disease (ibd) is increasing. this study aims to evaluate the diagnostic value of two serological markers, atypical perinuclear anti-neutrophil cytoplasmic antibodies (atypical-p-anca) and anti-saccharomyces cerevisiae antibodies (asca), with the intent to determinetheir relationship to ulcerative colitis (uc) and crohn's disease (cd), in...

there is the need for new drugs with better action and lesser side effects. a lot of research is being undertaken to find out new plant drugs, their extraction and pharmacological evaluation. one of such plant is curcuma aromatica whichbelongs to the genus curcuma and reported to have high ethno-botanical values in traditional medicine. the present study evaluates comparative pharmacological ac...

curcumin is a hydrophobic polyphenol and major bioactive component of turmeric with known anti-inflammatory, neurogenesis, antioxidant, and anti-carcinogenic effect. curcumin antagonizes many steps in the inflammatory cascade, including inhibition of nf-κb (nuclear factor kappa-light-chain-enhancer of activated b cells), activator protein-1 transcription and inos (induced nitric oxide synthases...

in the present study, the usage pattern of anti-inflammatory drugs-steroidal and non-steroidal- in patients referred to 13 aban pharmacy in sari was evaluated. the results show a high rate of anti-inflammatory drug prescriptions, mainly by general practitioners with ibuprofen, diclofenac and mefenamic acid being the most widely used nsaids and prednisolone, dexamethasone and betamethasone being...