Background and objectives: Dracocephalum species are mentioned in Iranian traditional medicine for enhancement of cognitive performance. In the present study, the acetyl cholinesterase inhibitory and butyryl cholinesterase inhibitory activities as well as the anti-oxidant and anti-tyrosinase effects of three Iranian Dracocephalum species (D. kotschyi,...

BACKGROUND People with dementia may be particularly sensitive to cognitive impairment induced by anticholinergic and sedative medicines. OBJECTIVE This study aimed to examine if utilisation of medicines with anticholinergic and sedative effects changed before and after initiation of anti-dementia therapy. METHODS A retrospective cohort study was conducted using Australian pharmacy claim dat...

The British Association for Psychopharmacology (BAP) coordinated a meeting of experts to review and revise its first (2006) Guidelines for clinical practice with anti-dementia drugs. As before, levels of evidence were rated using accepted standards which were then translated into grades of recommendation A to D, with A having the strongest evidence base (from randomized controlled trials) and D...

Clinical trials and independent reviews support the use of cholinesterase inhibitors for treating the symptoms of patients with mild to moderate Alzheimer's disease (AD). Before initiating cholinesterase inhibitor therapy, patients should be thoroughly assessed, and the diagnosis confirmed, preferably by a specialist. Compliance with cholinesterase inhibitor therapy should be monitored and the ...

In this study, the anti-cholinesterase activities of different extracts Achillea lycaonica, A. vermicularis and nobilis L. subsp. neilreichii (Kerner) Formanek species were examined then trace elements (Al, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Se, Cd, Pb) plants analysed by ICP-MS. The pharmacokinetic properties phenolic compounds these previously analyzed us ADME-Tox (absorption, distribution, m...

The crude extract of mangrove plant Rhizophora mucronata was prepared in this present work. The extract was testified for its anti-mosquito larvicidal property against two species of mosquito viz: Anopheles stephensi and Aedes aegypti. The 48 hours exposure of various dilutions of 100, 200, 300, 400, 500 ppm were given to the III to IV instar larval population. Percentage mortality data was ana...