A striking aspect of many vertebrate immune system is the exceptionally high level of polymorphism they harbor. A convincing case can be made that this polymorphism is driven by the diversity of pathogens that face selective pressures to evade attack by the host immune system. Different organisms accomplish a defense against diverse pathogens through mechanisms that differ widely in their requi...

Land use planning and ecological land evaluation are considered the most important tools and factors of sustainable development. Two aspects are of importance, firstly the potential suitability of the land for a specific use and the secondly management practices that integrate various factors such as agro-ecological aptitude, environmental impact, hydro-climate conditions and socioeconomic cons...

The atrial natriuretic peptide (ANP)-C receptor is generally believed to clear ANP; however, the ANP-C receptor may serve to reduce cAMP by inhibiting adenylate cyclase. ANP decreases endothelial permeability in coronary endothelial cell monolayers. We tested the hypothesis that part of this effect might be mediated by the ANP-C receptor. We used an endothelial cell monolayer from rat coronary ...

Three atrial natriuretic peptide (ANP) receptors, ANP(A), ANP(B), and ANP(C), have been identified in the heart, suggesting that natriuretic peptides may have direct effects on cardiac function. To characterize the possible role of atrial natriuretic peptide (ANP) in the regulation of its own secretion, we studied here the effects of ANP (greater affinity for ANP(A) than for ANP(B) receptors) a...

this research has been conducted with the aim of analyzing the spatial distribution of existing cultural land use in district 3 of tehran municipality and proposal for new site selection for cultural land use in this district. after studying previous researches on the issues of land use and site selection, 13 indicators for locating cultural land use were identified then by using distance mappi...

The identification of appropriate locations for wind energy development is a complex problem that involves several factors, ranging from technical to socio-economic and environmental aspects. Wind site selection generally associated with high degrees uncertainty due the long planning, design, construction, operational timescales. Thus, there crucial need develop efficient methods are capable ca...