The Diethyl ether fraction of the Methanolic extract of Annona senegalensis (Pers) stem bark was prepared in yield of (0.16%). Preparative Thin Layer Chromatography analysis of the fraction resulted in the identification of two spots with antimicrobial activity. Subsequent GC/MS analysis of these spots resulted in the identification of ten components (spot one) and fourteen components (spot two...

AIM OF THE STUDY To investigate the antidiarrhoeal properties of the stem-bark extract of Annona senegalensis, using both in vivo and in vitro models. MATERIALS AND METHODS Swiss albino mice were used to investigate the acute oral toxicity of the extract. The extract was administered orally to mice fed with charcoal meal in order to investigate intestinal transit time. The effect of the extra...

Annona squamosa is a medicinal plant which has been used in alternative medicine from ancient times. Different parts of Annona squamosa such as fruits, seeds, leaves and barks have been used to treat many diseases. Some of the active constituents have been identified and investigated for biological actions while the rest are yet to be explored. Current understanding of pharmacological propertie...

The aim of the present study is to determine the antioxidant, carotene and alkaloids content of the selected plant leaves namely spinach oleracea and Annona squamosa. The antioxidant screening was done by DPPH free radical scavenging assay using shade dried leaf extracts. The results showed that IC50 for Annona squamosa and Spinach oleracea was 68.24 (μg/ml), 42.57 μg/ml respectively. Annona sq...

Article history: Received on: 20/01/2015 Revised on: 18/02/2015 Accepted on: 21/03/2015 Available online: 15/05/2015 Annona squamosa and its active alkaloid content (-) Anonaine are known for antiepileptic activity on the basis of literature review. The objective of this study was to establish neuroprotection by Annona squamosa and its active alkaloid content (-) Anonaine as an antiepileptic ag...

Annona squamosa is a multipurpose tree with edible fruits and is a source of medicinal and industrial products. The alkaloids present in Annona squamosa, a medicinal plant has proved to have antioxidant activity. The present study has been designed to evaluate the hepatoprotective effect of custard apple (Annona squamosa) in Diethylnitrosamine (DEN) induced swiss albino mice. Analysis of select...

Annona muricata, commonly known as soursop, contains annonacin, acetogenin, and polyphenol which are known to have chemopreventive effects on cancer. In this study, we tend to evaluate the apoptosis-inducing effect of soursop (Annona muricata) leaf extract on the colorectal cancer cell line COLO-205 through the activities of caspase-3 which is a marker of cell apoptosis. Cell cultures were incu...