INTRODUCTION MOST methods of studying the effects of chemotherapeutic agents on tumours in the rat involve the ability to obtain a reproducible series of tumours in similar animals at the same time. This is done by transplanting portions of a suspension of cells prepared from a tumour in a donor animal to a series of host rats of the same breed. (Lucke et al., 1952, and Cole et al., 1956). The ...

Information on draught ability on all the major Indian breeds of cattle, buffaloes and pack animals including cross breeds is scanty available, because major research programme has been undertaken on milch animals. Similarly the scenario of cancer incidences in India is not much clear due to lack of systemic study at national level and absence of Animal Cancer Registry. In India, the incidence ...

background petro-clival, clival and spheno-petro-clival tumours are still a neurosurgical challenge. usually, the classical skull base transpetrous approaches are employed, although they are burdened by an important rate of morbidity, and a very low rate of radical removal is reported. conclusions anterior transoral and transsphenoidal approaches are indicated for clival and spheno-petro-clival...

Hepatocellular carcinoma is a common cancer in Asia with a poor prognosis. Tumour encapsulation has been shown to be a good, independent prognostic factor. The main cell in the liver responsible for extracellular matrix formation is the hepatic stellate cell, and this was investigated as the cell type responsible for encapsulation. This lecture discusses the role of hepatic stellate cells in he...

ewing sarcoma is about 10 % of bone tumours, in the form of lytic, sclerotic and mixed type. the lytic type erodes the whole bone in such a way that the auther would like to name it 'vanishing' type and recognition of this radiological type is of great importance from differential point of view in the study of primary and secondry tumours of bones.

BACKGROUND: In the present study, the submandibularsalivary gland microscopic morphology of the adult Africangiant pouched rat was investigated. This study was carried out toprovide the basic histology of this organ in the giant pouched rat,to accompany the dearth of information of its microscopicarchitecture in the available literature. This becomes of evenhigher importance when considering th...

Radiofrequecy ablation is the most widely used local ablative therapy for both primary and metastatic liver tumours. However, it has limited application in the treatment of large tumours (tumours >3cm) and multicentric tumours. In recent years, many strategies have been developed to extend the application of radiofrequency ablation to large tumours. A promising approach is to take advantage of ...

Oligodeoxynucleotides containing guanine-cytidine dimers (CpG ODN) are potent inducers of anti-tumour immune responses. In this study, we analyzed the capacity of CpG ODN to inhibit the growth of both MHC class I-positive and -deficient tumours after debulking the tumour mass by chemotherapy or surgery. We employed an animal model resembling human papillomavirus (HPV) 16-associated tumours. Tum...