Glaucoma, a group of heterogeneous optic neuropathies characterized by progressive visual field loss, is the leading cause of irreversible blindness worldwide. The condition has a substantial heritable basis, as illustrated by the numerous loci and genes identified to date, and the large proportion of patients having a family history. Categorized according to the anatomy of the anterior chamber...

PURPOSE To investigate the differences in the histopathology and matrix metalloproteinase (MMP) expression in the Tenon's tissue of primary open-angle glaucoma (POAG) patients, primary angle-closure glaucoma (PACG) patients, and non-glaucomatous patients. METHODS POAG and PACG patients, who underwent a trabeculectomy and had no history of ocular disease except glaucoma, were enrolled. The num...

Glaucoma is a complex genetic optic disease characterized by a range of optic neuropathies. There are many subtypes of glaucoma but primary open-angle glaucoma (POAG) associated with elevated intraocular pressure (IOP) is the most prevalent form. Based on the age of diagnosis, POAG is categorized as early-onset POAG or juvenile open-angle glaucoma (JOAG) diagnosed between 10 and 35 years and ad...

purpose: to evaluate visual outcomes and intraocular pressure (iop) after single-site phacotrabeculectomy with mitomycin c in patients with senile cataract and primary open angle glaucoma (poag), pseudoexfoliative glaucoma (pxg), or chronic angle closure glaucoma (cacg). methods: in this retrospective study, patients older than 50 years who had significant cataracts (bcva £ 20/60) and uncontrol...

We describe the prevalence and treatment of glaucoma in a Muslim Arab population in Israel. Based on the medical records of 15 122 persons, the overall prevalence of glaucoma was 3.9%. Prevalence rates of primary open angle glaucoma (POAG) and primary angle-closure glaucoma (PACG) were 3.0% and 0.42%, respectively. Prevalence rates of women were 135% that of men considering all types of glaucom...

Purpose : to summarize the experience of development and application artificial neural networks (ANW) in early diagnosis primary open-angle glaucoma (POAG). Material methods . A total 690 patients (918 eyes) were tested. The training clinical group consisted 459 examples (459 eyes), which 369 eyes had an initial stage POAG 90 no glaucoma. testing was represented by 131 (131 110 belonged with 21...

results we identified no mutations in these patients in the three screened positions. conclusions to ensure that these genes play no role in the disease, evaluation of the non-coding regions of both the cyp1b1 and myoc genes is strongly recommended, since other genes are involved in the pathogenesis of glaucoma. patients and methods forty patients with poag were recruited from the ophthalmic di...

PURPOSE Primary open-angle glaucoma (POAG) is the predominant form of chronic glaucoma, but the underlying pathologic mechanisms are largely unknown. Because prostaglandins (PGs) have been introduced into POAG treatment with remarkable success, this study was undertaken to investigate whether a change in the expression of the PG-synthesizing enzymes cyclooxygenase (COX)-1 and -2 might be involv...

PURPOSE To quantitatively analyze central corneal thickness (CCT) in patients with primary angle closure glaucoma (PACG) and primary open-angle glaucoma (POAG), and to evaluate its correlation with severity of glaucoma. METHODS In this retrospective study, records of patients with previously diagnosed POAG or PACG at a tertiary glaucoma service were reviewed. CCT was measured by ultrasound pa...

BACKGROUND To compare retinal vessel oxygenation and vessel caliber in primary angle-closure glaucoma (PACG), primary open-angle glaucoma (POAG), normal-tension glaucoma (NTG), and normal controls, as well as between eyes of asymmetrical glaucoma severity. METHODS This was a prospective, cross-sectional study. The 159 subjects (PACG, n=39; POAG, n=41; NTG, n=41; normal controls, n=38) underwe...