BACKGROUND Hemodynamic insults at arterial bifurcations are believed to play a critical role in initiating intracranial aneurysms. Recent studies in a rabbit model indicate that aneurysmal damage initiates under specific wall shear stress conditions when smooth muscle cells (SMCs) become pro-inflammatory and produce matrix metalloproteinases (MMPs). The mechanisms leading to SMC activation and ...

The authors reviewed a consecutive series of 115 patients who underwent common carotid ligation during the period 1954-1984. Average follow-up was 10 years. Seventy-three (63%) patients presented following a subarachnoid haemorrhage (SAH) and 42 (36%) presented with the mass effect of an unruptured aneurysm. Thirty-nine (34%) patients were lost to follow-up of whom 27 had had a previous SAH. Fo...

Superior mesenteric artery (SMA) aneurysm is a rare disease. In this case report, we present a 32 years old woman who was admitted to our hospital with chronic abdominal pain. SMA aneurysm was diagnosed after radiological evaluation. The patient underwent ligation of the superior mesenteric artery aneurysm and remained well 12 months after the surgery.

A 47-year-old woman complained of abdominal pain, and a computed tomography scan indicated compressive obstruction of the celiac axis and a 4-cm retropancreatic aneurysm. An angiogram identified the aneurysmal vessel as the posterior pancreaticoduodenal artery. All foregut structures were supplied by this aneurysmal vessel. Via an open approach, the inflow and outflow of the aneurysm were ligat...

UNLABELLED BRIEF SUMMARY: We describe the use of adenosine-induced cardiac arrest to facilitate intracranial aneurysm clip ligation. BACKGROUND Cerebral aneurysms are highly variable which may result in difficult surgical exposure for clip ligation in select cases. Secure clip placement is often not feasible without temporarily decompressing the aneurysm. This can be accomplished with tempora...

OBJECTIVES To establish a cost-effective and reproducible procedure for induction of chronic left ventricular aneurysm (LVA) in rabbits. METHODS Acute myocardial infarction (AMI) was induced in 35 rabbits via concomitant ligation of the left anterior descending (LAD) coronary artery and the circumflex (Cx) branch at the middle portion. Development of AMI was confirmed by ST segment elevation ...

A patient with cervicocranial fibromuscular dysplasia (FMD) presented with subarachnoid hemorrhage. A ruptured dissecting distal vertebral artery aneurysm required clip ligation of the parent artery; a contralateral dissecting proximal vertebral aneurysm was occluded with detachable coils. Progressive dissecting, extracranial aneurysms of the internal carotid artery were treated with self-expan...

Superior mesenteric artery (SMA) aneurysm is a rare disease. In this case report, we present a 32 years old woman who was admitted to our hospital with chronic abdominal pain. SMA aneurysm was diagnosed after radiological evaluation. The patient underwent ligation of the superior mesenteric artery aneurysm and remained well 12 months after the surgery. © 2011 Tehran University of Medical Scienc...

INTRODUCTION Ruptured common iliac aneurysms present with diagnostic and therapeutic challenges. This case describes the successful outcome in a patient with complex vascular surgical history. CASE PRESENTATION An elderly patient presented with abdominal pain confirmed by CT as leaking iliac aneurysm. He had previously undergone an aorto-bifemoral bypass graft for ruptured abdominal aortic an...

Parent artery ligation is an accepted treatment for intracranial aneurysms that are not amenable to a direct surgical approach. Parent artery ligation is one of the oldest effective surgical means of aneurysm therapy (the "Hunterian principle" (1 ]). Recently it has become possible to perform parent artery occlusion of the carotid or vertebral artery percutaneously by using detachable balloon t...